EC 2.6.1.12 - Alanine—oxo-acid transaminase

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IntEnz Enzyme Nomenclature
EC 2.6.1.12

Names

Accepted name:
alanine—oxo-acid transaminase
Other names:
L-alanine—α-keto acid aminotransferase
alanine—keto acid aminotransferase
alanine—oxo acid aminotransferase
leucine—alanine transaminase
alanine—oxo-acid aminotransferase
Systematic name:
L-alanine:2-oxo-acid aminotransferase

Reaction

Cofactor

Comments:

A pyridoxal-phosphate protein.

Links to other databases

Enzymes and pathways: NC-IUBMB , BRENDA , DIAGRAM , DIAGRAM , ExplorEnz , ENZYME@ExPASy , KEGG , MetaCyc , UniPathway
Structural data: CSA , EC2PDB
Gene Ontology: GO:0047635
CAS Registry Number: 9030-41-5

References

  1. Altenbern, R.A. and Housewright, R.D.
    Transaminases in smooth Brucella abortus, strain 19.
    J. Biol. Chem. 204: 159-167 (1953). [PMID: 13084587]
  2. Rowsell, E.V.
    Transaminations with pyruvate and other α-keto acids.
    Biochem. J. 64: 246-252 (1956). [PMID: 13363834]
  3. Sallach, H.J.
    Formation of serine from hydroxypyruvate and L-alanine.
    J. Biol. Chem. 223: 1101-1108 (1956). [PMID: 13385257]
  4. Wilson, D.G., King, K.W. and Burris, R.H.
    Transaminase reactions in plants.
    J. Biol. Chem. 208: 863-874 (1954). [PMID: 13174595]

[EC 2.6.1.12 created 1961]