EC 2.5.1.75 - TRNA dimethylallyltransferase

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IntEnz Enzyme Nomenclature
EC 2.5.1.75

Names

Accepted name:
tRNA dimethylallyltransferase
Other names:
Δ2-isopentenyl pyrophosphate:tRNA-Δ2-isopentenyl transferase [incorrect]
Δ2-isopentenyl pyrophosphate:transfer ribonucleic acid Δ2-isopentenyltransferase [incorrect]
transfer ribonucleate isopentenyltransferase [incorrect]
IPP transferase [incorrect]
tRNA prenyltransferase
MiaA
Systematic name:
dimethylallyl-diphosphate:tRNA dimethylallyltransferase

Reaction

Comments:

Formerly known as tRNA isopentenyltransferase (EC 2.5.1.8), but it is now known that dimethylallyl diphosphate, rather than isopentenyl diphosphate, is the substrate. Formerly EC 1.8.6.1 and EC 2.5.1.8.

Links to other databases

Enzymes and pathways: NC-IUBMB , BRENDA , ExplorEnz , ENZYME@ExPASy , KEGG , MetaCyc , UniPathway
Structural data: CSA , EC2PDB
Gene Ontology: GO:0052381
CAS Registry Number: 37277-78-4
UniProtKB/Swiss-Prot: (792) [show] [UniProt]

References

  1. Leung, H. C., Chen, Y., Winkler, M. E.
    Regulation of substrate recognition by the MiaA tRNA prenyltransferase modification enzyme of Escherichia coli K-12.
    J. Biol. Chem. 272: 13073-13083 (1997). [PMID: 9148919]
  2. Soderberg, T., Poulter, C. D.
    Escherichia coli dimethylallyl diphosphate:tRNA dimethylallyltransferase: essential elements for recognition of tRNA substrates within the anticodon stem-loop.
    Biochemistry 39: 6546-6553 (2000). [PMID: 10828971]
  3. Moore, J. A., Mathis, J. R., Poulter, C. D.
    Escherichia coli dimethylallyl diphosphate:tRNA dimethylallyltransferase: pre-steady-state kinetic studies.
    Biochim. Biophys. Acta 1479: 166-174 (2000). [PMID: 11004538]

[EC 2.5.1.75 created 1972 as EC 2.5.1.8, transferred 2009 to EC 2.5.1.75]