EC - 15-cis-phytoene synthase

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IntEnz Enzyme Nomenclature


Accepted name:
15-cis-phytoene synthase
Other names:
geranylgeranyl-diphosphate geranylgeranyltransferase [ambiguous]
phytoene synthetase [ambiguous]
prephytoene-diphosphate synthase [ambiguous]
PSase [ambiguous]
Systematic name:
geranylgeranyl-diphosphate:geranylgeranyl-diphosphate geranylgeranyltransferase (15-cis-phytoene forming)




Requires Mn2+ for activity. The enzyme produces 15-cis-phytoene. cf. EC, 15-trans-phytoene synthase.

Links to other databases

Enzymes and pathways: NC-IUBMB , BRENDA , DIAGRAM , ExplorEnz , ENZYME@ExPASy , KEGG , MetaCyc , UniPathway
Structural data: CSA , EC2PDB
Gene Ontology: GO:0016767
CAS Registry Numbers: 50936-61-3 57219-66-6
UniProtKB/Swiss-Prot: (32) [show] [UniProt]


  1. Gregonis, D.E. and Rilling, H.C.
    The stereochemistry of trans-phytoene synthesis. Some observations on lycopersene as a carotene precursor and a mechanism for the synthesis of cis- and trans-phytoene.
    Biochemistry 13: 1538-1542 (1974). [PMID: 4819767]
  2. Misawa, N., Truesdale, M.R., Sandmann, G., Fraser, P.D., Bird, C., Schuch, W. and Bramley, P.M.
    Expression of a tomato cDNA coding for phytoene synthase in Escherichia coli, phytoene formation in vivo and in vitro, and functional analysis of the various truncated gene products.
    J. Biochem. (Tokyo) 116: 980-985 (1995). [PMID: 7896759]

[EC created 1984, modified 2005, modified 2012]