EC 2.5.1.29 - Geranylgeranyl diphosphate synthase

  IntEnz view ENZYME view

IntEnz Enzyme Nomenclature
EC 2.5.1.29

Names

Accepted name:
geranylgeranyl diphosphate synthase
Other names:
farnesyltransferase
geranylgeranyl pyrophosphate synthase
geranylgeranyl pyrophosphate synthetase
geranylgeranyl-PP synthetase
geranylgeranyl-diphosphate synthase
farnesyltranstransferase [obsolete]
Systematic name:
(2E,6E)-farnesyl-diphosphate:isopentenyl-diphosphate farnesyltranstransferase

Reaction

Comments:

Some forms of this enzyme will also use geranyl diphosphate and dimethylallyl diphosphate as donors; it will not use larger prenyl diphosphates as efficient donors.

Links to other databases

Enzymes and pathways: NC-IUBMB , BRENDA , DIAGRAM , ExplorEnz , ENZYME@ExPASy , KEGG , MetaCyc , UniPathway
Protein domains and families: PROSITE:PDOC00407
Structural data: CSA , EC2PDB
Gene Ontology: GO:0004311
CAS Registry Number: 9032-58-0
UniProtKB/Swiss-Prot: (48) [show] [UniProt]

References

  1. Sagami, H., Ishi, K. and Ogura, K.
    Occurrence and unusual properties of geranylgeranyl pyrophosphate synthetase of pig liver.
    Biochem. Int. 3: 669-675 (1981).

[EC 2.5.1.29 created 1984, modifed 2011]