EC 2.5.1.26 - Alkylglycerone-phosphate synthase

  IntEnz view ENZYME view

IntEnz Enzyme Nomenclature
EC 2.5.1.26

Names

Accepted name:
alkylglycerone-phosphate synthase
Other names:
DHAP-AT
alkyl DHAP synthetase
alkyl-DHAP
alkyldihydroxyacetone phosphate synthetase
alkyldihydroxyacetonephosphate synthase
dihydroxyacetone-phosphate acyltransferase
alkyl-DHAP synthase
Systematic name:
1-acyl-glycerone-3-phosphate:long-chain-alcohol O-3-phospho-2-oxopropanyltransferase

Reaction

Comments:

The ester-linked fatty acid of the substrate is cleaved and replaced by a long-chain alcohol in an ether linkage.

Links to other databases

Enzymes and pathways: NC-IUBMB , BRENDA , ExplorEnz , ENZYME@ExPASy , KEGG , MetaCyc , UniPathway
Structural data: CSA , EC2PDB
Gene Ontology: GO:0008609
UniProtKB/Swiss-Prot:

References

  1. Brown, A.J. and Snyder, F.
    Alkyldihydroxyacetone-P synthase. Solubilization, partial purification, new assay method, and evidence for a ping-pong mechanism.
    J. Biol. Chem. 257: 8835-8839 (1982). [PMID: 7096336]
  2. Wykle, R.L., Piantadosi, C. and Snyder, F.
    The role of acyldihydroxyacetone phosphate, reduced nicotinamide adenine dinucleotide, and reduced nicotinamide adenine dinucleotide phosphate in the biosynthesis of O-alkyl glycerolipids by microsomal enzymes of Ehrlich ascites tumor.
    J. Biol. Chem. 247: 2944-2948 (1972). [PMID: 4401994]

[EC 2.5.1.26 created 1984]