EC 2.4.2.14 - Amidophosphoribosyltransferase

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IntEnz Enzyme Nomenclature
EC 2.4.2.14

Names

Accepted name:
amidophosphoribosyltransferase
Other names:
5'-phosphoribosylpyrophosphate amidotransferase
5-phosphoribosyl-1-pyrophosphate amidotransferase
5-phosphororibosyl-1-pyrophosphate amidotransferase
α-5-phosphoribosyl-1-pyrophosphate amidotransferase
glutamine 5-phosphoribosylpyrophosphate amidotransferase
glutamine phosphoribosyldiphosphate amidotransferase
glutamine ribosylpyrophosphate 5-phosphate amidotransferase
phosphoribose pyrophosphate amidotransferase
phosphoribosyl pyrophosphate amidotransferase
phosphoribosyldiphosphate 5-amidotransferase
phosphoribosylpyrophosphate glutamyl amidotransferase
glutamine phosphoribosylpyrophosphate amidotransferase
5-phosphoribosylamine:diphosphate phospho-α-D-ribosyltransferase (glutamate-amidating)
Systematic name:
5-phospho-β-D-ribosylamine:diphosphate phospho-α-D-ribosyltransferase (glutamate-amidating)

Reaction

Links to other databases

Enzymes and pathways: NC-IUBMB , BRENDA , DIAGRAM , ExplorEnz , ENZYME@ExPASy , KEGG , MetaCyc , UniPathway
Protein domains and families: PROSITE:PDOC00096 , PROSITE:PDOC00406
Structural data: CSA , EC2PDB
Gene Ontology: GO:0004044
CAS Registry Number: 9031-82-7
UniProtKB/Swiss-Prot: (40) [show] [UniProt]

References

  1. Caskey, C.T., Ashton, D.M. and Wyngaarden, J.B.
    The enzymology of feedback inhibition of glutamine phosphoribosylpyrophosphate amidotransferase by purine ribonucleotides.
    J. Biol. Chem. 239: 2570-2579 (1964). [PMID: 14235537]
  2. Hartman, S.C. and Buchanan, J.M.
    Biosynthesis of the purines. XXI. 5-Phosphoribosylpyrophosphate amidotransferase.
    J. Biol. Chem. 233: 451-455 (1958). [PMID: 13563519]

[EC 2.4.2.14 created 1961]