EC 2.4.1.83 - Dolichyl-phosphate β-D-mannosyltransferase

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IntEnz Enzyme Nomenclature
EC 2.4.1.83

Names

Accepted name:
dolichyl-phosphate β-D-mannosyltransferase
Other names:
GDP-mannose-dolichol phosphate mannosyltransferase
GDPMan:DolP mannosyltransferase
GDPmannose-dolichylmonophosphate mannosyltransferase
GDPmannose:dolichyl-phosphate mannosyltransferase
dolichol phosphate mannose synthase
dolichyl mannosyl phosphate synthase
dolichyl phosphate mannosyltransferase
dolichyl-phosphate mannose synthase
dolichyl-phospho-mannose synthase
guanosine diphosphomannose-dolichol phosphate mannosyltransferase
mannosylphosphodolichol synthase
mannosylphosphoryldolichol synthase
Systematic name:
GDP-mannose:dolichyl-phosphate β-D-mannosyltransferase

Reaction

Comments:

Acts only on long-chain polyprenyl phosphates and α-dihydropolyprenyl phosphates that are larger than C35.

Links to other databases

Enzymes and pathways: NC-IUBMB , BRENDA , ExplorEnz , ENZYME@ExPASy , KEGG , MetaCyc , UniPathway
Structural data: CSA , EC2PDB
Gene Ontology: GO:0004582
CAS Registry Number: 62213-44-9
UniProtKB/Swiss-Prot: (14) [show] [UniProt]

References

  1. Babczinski, P., Haselbeck, A. and Tanner, W.
    Yeast mannosyl transferases requiring dolichyl phosphate and dolichyl phosphate mannose as substrate. Partial purification and characterization of the solubilized enzyme.
    Eur. J. Biochem. 105: 509-515 (1980). [PMID: 6989607]
  2. Bretthauer, R.K., Wu, S. and Irwin, W.E.
    Enzymatic transfer of mannose from guanosine diphosphate mannose to dolichol phosphate in yeast (Hansenula holstii). A possible step in mannan synthesis.
    Biochim. Biophys. Acta 304: 736-747 (1973). [PMID: 4726855]
  3. Haselbeck, A.
    Purification of GDP mannose:dolichyl-phosphate O-β-D-mannosyltransferase from Saccharomyces cerevisiae.
    Eur. J. Biochem. 181: 663-668 (1989). [PMID: 2659345]
  4. Palamarczyk, G., Lehle, L., Mankowski, T., Chojnacki, T. and Tanner, W.
    Specificity of solubilized yeast glycosyl transferases for polyprenyl derivatives.
    Eur. J. Biochem. 105: 517-523 (1980). [PMID: 6445267]
  5. Richards, J.B. and Hemming, F.W.
    The transfer of mannose from guanosine diphosphate mannose to dolichol phosphate and protein by pig liver endoplasmic reticulum.
    Biochem. J. 130: 77-93 (1972). [PMID: 4655455]

[EC 2.4.1.83 created 1976, modified 1983]