EC 2.4.1.21 - Starch synthase

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IntEnz Enzyme Nomenclature
EC 2.4.1.21

Names

Accepted name:
starch synthase
Other names:
ADP-glucose starch synthase
ADP-glucose synthase
ADP-glucose transglucosylase
ADP-glucose-starch glucosyltransferase
ADPG starch synthetase
ADPG-starch glucosyltransferase
ADPglucose-starch glucosyltransferase
ADPglucose:1,4-α-D-glucan 4-α-D-glucosyltransferase
adenosine diphosphate glucose-starch glucosyltransferase
adenosine diphosphoglucose-starch glucosyltransferase
starch synthetase
starch (bacterial glycogen) synthase
glycogen synthase
ADP-glucose—starch glucosyltransferase
ADP-glucose:1,4-α-D-glucan 4-α-D-glucosyltransferase
Systematic name:
ADP-α-D-glucose:(1→4)-α-D-glucan 4-α-D-glucosyltransferase

Reaction

Comments:

The accepted name varies according to the source of the enzyme and the nature of its synthetic product, e.g. starch synthase, bacterial glycogen synthase. Similar to EC 2.4.1.11 [glycogen(starch) synthase] but the preferred or mandatory nucleoside diphosphate sugar substrate is ADP-α-D-glucose. The entry covers starch and glycogen synthases utilizing ADP-α-D-glucose.

Links to other databases

Enzymes and pathways: NC-IUBMB , BRENDA , ExplorEnz , ENZYME@ExPASy , KEGG , MetaCyc , UniPathway
Structural data: CSA , EC2PDB
Gene Ontology: GO:0033201 , GO:0009011
CAS Registry Number: 9030-10-8
UniProtKB/Swiss-Prot: (394) [show] [UniProt]

References

  1. Chambers, J.C. and Elbein, A.D.
    Biosynthesis of glucans in mung bean seedlings. Formation of β-(1,4)-glucans from GDP-glucose and β-(1,3)-glucans from UDP-glucose.
    Arch. Biochem. Biophys. 138: 620-631 (1970). [PMID: 4317490]
  2. Frydman, R.B. and Cardini, C.E.
    Studies on adenosine diphosphate D-glucose: α-1,4-glucan α-4-glucosyltransferase of sweet-corn endosperm.
    Biochim. Biophys. Acta 96: 294-303 (1965).
  3. Greenberg, E. and Preiss, J.
    Biosynthesis of bacterial glycogen. II. Purification and properties of the adenosine diphosphoglucose:glycogen transglucosylase of arthrobacter species NRRL B1973.
    J. Biol. Chem. 240: 2341-2348 (1965).
  4. Leloir, L.F., de Fekete, M.A. and Cardini, C.E.
    Starch and oligosaccharide synthesis from uridine diphosphate glucose.
    J. Biol. Chem. 236: 636-641 (1961).
  5. Preiss, J., Govins, S., Eidels, L., Lammel, C., Greenberg, E., Edelmann, P. and Sabraw, A.
    Regulatory mechanisms in the biosynthesis of α-1,4-glucans in bacteria and plants.
    In: Whelan, W.J. and Schultz, J (Eds.) Miami Winter Symposia vol. 1, North Holland, Utrecht, 1970, 122-138

[EC 2.4.1.21 created 1965]