EC 2.4.1.12 - Cellulose synthase (UDP-forming)

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IntEnz Enzyme Nomenclature
EC 2.4.1.12

Names

Accepted name:
cellulose synthase (UDP-forming)
Other names:
1,4-β-D-glucan synthase
1,4-β-glucan synthase
β-1,4-glucan synthase
β-1,4-glucan synthetase
β-1,4-glucosyltransferase
β-glucan synthase
GS-I
UDP-glucose-1,4-β-glucan glucosyltransferase
UDP-glucose—β-glucan glucosyltransferase
UDP-glucose-cellulose glucosyltransferase
glucan synthase
uridine diphosphoglucose-1,4-β-glucan glucosyltransferase
uridine diphosphoglucose-cellulose glucosyltransferase
UDP-glucose-β-D-glucan glucosyltransferase
UDP-glucose:1,4-β-D-glucan 4-β-D-glucosyltransferase
UDP-glucose:(1→4)-β-D-glucan 4-β-D-glucosyltransferase
Systematic name:
UDP-α-D-glucose:(1→4)-β-D-glucan 4-β-D-glucosyltransferase (configuration-inverting)

Reaction

Comments:

Involved in the synthesis of cellulose. A similar enzyme utilizes GDP-glucose [EC 2.4.1.29 cellulose synthase (GDP-forming)].

Links to other databases

Enzymes and pathways: NC-IUBMB , BRENDA , ExplorEnz , ENZYME@ExPASy , KEGG , MetaCyc , UniPathway
Structural data: CSA , EC2PDB
Gene Ontology: GO:0016760
CAS Registry Number: 9027-19-4
UniProtKB/Swiss-Prot: (40) [show] [UniProt]

References

  1. Glaser, L.
    The synthesis of cellulose in cell-free extracts of Acetobacter xylinum.
    J. Biol. Chem. 232: 627-636 (1958). [PMID: 13549448]

[EC 2.4.1.12 created 1961]