EC 2.4.1.117 - Dolichyl-phosphate β-glucosyltransferase

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IntEnz Enzyme Nomenclature
EC 2.4.1.117

Names

Accepted name:
dolichyl-phosphate β-glucosyltransferase
Other names:
UDP-glucose dolichyl-phosphate glucosyltransferase
UDP-glucose:dolichol phosphate glucosyltransferase
UDP-glucose:dolicholphosphoryl glucosyltransferase
UDP-glucose:dolichyl monophosphate glucosyltransferase
UDP-glucose:dolichyl phosphate glucosyltransferase
UDPglucose:dolichyl-phosphate β-D-glucosyltransferase
polyprenyl phosphate:UDP-D-glucose glucosyltransferase
uridine diphosphoglucose-dolichol glucosyltransferase
UDP-glucose:dolichyl-phosphate β-D-glucosyltransferase
Systematic name:
UDP-α-D-glucose:dolichyl-phosphate β-D-glucosyltransferase (configuration-inverting)

Reaction

Comments:

Solanesyl phosphate and ficaprenyl phosphate can act as acceptors, but more slowly.

Links to other databases

Enzymes and pathways: NC-IUBMB , BRENDA , ExplorEnz , ENZYME@ExPASy , KEGG , MetaCyc , UniPathway
Structural data: CSA , EC2PDB
Gene Ontology: GO:0004581
CAS Registry Number: 71061-42-2
UniProtKB/Swiss-Prot: (11) [show] [UniProt]

References

  1. Behrens, N.H. and Leloir, L.F.
    Dolichol monophosphate glucose: an intermediate in glucose transfer in liver.
    Proc. Natl. Acad. Sci. USA 66: 153-159 (1970). [PMID: 5273893]
  2. Herscovics, A., Bugge, B. and Jeanloz, R.W.
    Glucosyltransferase activity in calf pancreas microsomes. Formation of dolichyl D[14C]glucosyl phosphate and 14C-labeled lipid-linked oligosaccharides from UDP-D-[14C]glucose.
    J. Biol. Chem. 252: 2271-2277 (1977). [PMID: 849929]
  3. Villemez, C.L. and Carlo, P.L.
    Properties of a soluble polyprenyl phosphate: UDP-D-glucose glucosyltransferase.
    J. Biol. Chem. 254: 4814-4819 (1979). [PMID: 438216]

[EC 2.4.1.117 created 1984]