EC 2.3.2.4 - γ-glutamylcyclotransferase

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IntEnz Enzyme Nomenclature
EC 2.3.2.4

Names

Accepted name:
γ-glutamylcyclotransferase
Other names:
γ-L-glutamylcyclotransferase
γ-glutamyl-amino acid cyclotransferase
L-glutamic cyclase
(5-L-glutamyl)-L-amino-acid 5-glutamyltransferase (cyclizing)
Systematic name:
(γ-L-glutamyl)-L-amino-acid γ-glutamyltransferase (cyclizing)

Reaction

Comments:

The enzyme acts on derivatives of L-glutamate, L-2-aminobutanoate, L-alanine and glycine.

Links to other databases

Enzymes and pathways: NC-IUBMB , BRENDA , ExplorEnz , ENZYME@ExPASy , KEGG , MetaCyc , UniPathway
Structural data: CSA , EC2PDB
Gene Ontology: GO:0003839
CAS Registry Number: 9045-44-7
UniProtKB/Swiss-Prot: (14) [show] [UniProt]

References

  1. Bodnaryk, R.P. and McGirr, L.
    Purification, properties and function of a unique γ-glutamyl cyclotransferase from the housefly, Musca domestica L.
    Biochim. Biophys. Acta 315: 352-362 (1973).
  2. Orlowski, M., Richman, P.G. and Meister, A.
    Isolation and properties of γ-L-glutamylcyclotransferase from human brain.
    Biochemistry 8: 1048-1055 (1969).

[EC 2.3.2.4 created 1972]