EC 2.3.1.74 - Naringenin-chalcone synthase

  IntEnz view ENZYME view

IntEnz Enzyme Nomenclature
EC 2.3.1.74

Names

Accepted name:
naringenin-chalcone synthase
Other names:
6'-deoxychalcone synthase
CHS
DOCS
chalcone synthase
chalcone synthetase
flavanone synthase
Systematic name:
malonyl-CoA:4-coumaroyl-CoA malonyltransferase (cyclizing)

Reaction

Comments:

In the presence of NADH and a reductase, 6'-deoxychalcone is produced.

Links to other databases

Enzymes and pathways: NC-IUBMB , BRENDA , DIAGRAM , ExplorEnz , ENZYME@ExPASy , KEGG , MetaCyc , UniPathway
Protein domains and families: PROSITE:PDOC00403
Structural data: CSA , EC2PDB
Gene Ontology: GO:0016210
CAS Registry Number: 56803-04-4
UniProtKB/Swiss-Prot: (134) [show] [UniProt]

References

  1. Ayabe, S.-I., Udagawa, A. and Furuya, T.
    NAD(P)H-dependent 6'-deoxychalcone synthase activity in Glycyrrhiza echinata cells induced by yeast extract.
    Arch. Biochem. Biophys. 261: 458-462 (1988). [PMID: 3355160]
  2. Heller, W. and Hahlbrock, K.
    Highly purified "flavanone synthase" from parsley catalyzes the formation of naringenin chalcone.
    Arch. Biochem. Biophys. 200: 617-619 (1980). [PMID: 7436427]

[EC 2.3.1.74 created 1984]