EC - Diamine N-acetyltransferase

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IntEnz Enzyme Nomenclature


Accepted name:
diamine N-acetyltransferase
Other names:
acetyl-coenzyme A-1,4-diaminobutane N-acetyltransferase
diamine acetyltransferase
putrescine (diamine)-acetylating enzyme
putrescine N-acetyltransferase
putrescine acetylase
putrescine acetyltransferase
spermidine N1-acetyltransferase
spermidine acetyltransferase
spermidine/spermine N1-acetyltransferase
Systematic name:
acetyl-CoA:alkane-α,ω-diamine N-acetyltransferase



Acts on 1,3-diaminopropane, 1,5-diaminopentane, putrescine, spermidine (forming N1- and N8-acetylspermidine), spermine, N1-acetylspermidine and N8-acetylspermidine.

Links to other databases

Enzymes and pathways: NC-IUBMB , BRENDA , ExplorEnz , ENZYME@ExPASy , KEGG , MetaCyc , UniPathway
Structural data: CSA , EC2PDB
Gene Ontology: GO:0004145
CAS Registry Number: 54596-36-0
UniProtKB/Swiss-Prot: (20) [show] [UniProt]


  1. Della Ragione, F. and Pegg, A.E.
    Purification and characterization of spermidine/spermine N1-acetyltransferase from rat liver.
    Biochemistry 21: 6152-6158 (1982). [PMID: 7150547]

[EC created 1976, modified 1989]