EC 2.3.1.5 - Arylamine N-acetyltransferase

  IntEnz view ENZYME view

IntEnz Enzyme Nomenclature
EC 2.3.1.5

Names

Accepted name:
arylamine N-acetyltransferase
Other names:
2-naphthylamine N-acetyltransferase
4-aminobiphenyl N-acetyltransferase
N-acetyltransferase
β-naphthylamine N-acetyltransferase
p-aminosalicylate N-acetyltransferase
acetyl CoA-arylamine N-acetyltransferase
arylamine acetylase
arylamine acetyltransferase
indoleamine N-acetyltransferase
serotonin N-acetyltransferase
Systematic name:
acetyl-CoA:arylamine N-acetyltransferase

Reaction

Comments:

Wide specificity for aromatic amines, including serotonin; also catalyses acetyl-transfer between arylamines without CoA.

Links to other databases

Enzymes and pathways: NC-IUBMB , BRENDA , ExplorEnz , ENZYME@ExPASy , KEGG , MetaCyc , NIST 74 , UM-BBD , UniPathway
Structural data: CSA , EC2PDB
Gene Ontology: GO:0004060
CAS Registry Number: 9027-33-2
UniProtKB/Swiss-Prot: (24) [show] [UniProt]

References

  1. Chou, T.C. and Lipmann, F.
    Separation of acetyl transfer enzymes in pigeon liver extract.
    J. Biol. Chem. 196: 89-103 (1952). [PMID: 12980945]
  2. Paul, R.C. and Ratledge, C.
    Further studies on anthranilate N-acetyltransferase and the metabolism of N-acetylanthranilic acid in Aerobacter aerogenes.
    Biochim. Biophys. Acta 320: 9-15 (1973). [PMID: 4748369]
  3. Tabor, H., Mehler, A.H. and Stadtman, E.R.
    The enzymatic acetylation of amines.
    J. Biol. Chem. 204: 127-138 (1953). [PMID: 13084583]
  4. Weissbach, H., Redfield, B.G. and Axelrod, J.
    The enzymic acetylation of serotonin and other naturally occurring amines.
    Biochim. Biophys. Acta 54: 190-192 (1961). [PMID: 14005907]

[EC 2.3.1.5 created 1961, modified now]