EC 2.3.1.42 - Glycerone-phosphate O-acyltransferase

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IntEnz Enzyme Nomenclature
EC 2.3.1.42

Names

Accepted name:
glycerone-phosphate O-acyltransferase
Other name:
dihydroxyacetone phosphate acyltransferase
Systematic name:
acyl-CoA:glycerone-phosphate O-acyltransferase

Reaction

Comments:

A membrane protein. Uses CoA derivatives of palmitate, stearate and oleate, with highest activity on palmitoyl-CoA.

Links to other databases

Enzymes and pathways: NC-IUBMB , BRENDA , ERGO , ExplorEnz , ENZYME@ExPASy , KEGG , MetaCyc , UniPathway
Structural data: CSA , EC2PDB
Gene Ontology: GO:0016287
CAS Registry Number: 37257-19-5
UniProtKB/Swiss-Prot:

References

  1. Ballas, L.M. and Bell, R.M.
    Topography of glycerolipid synthetic enzymes. Synthesis of phosphatidylserine, phosphatidylinositol and glycerolipid intermediates occurs on the cytoplasmic surface of rat liver microsomal vesicles.
    Biochim. Biophys. Acta 665: 586-595 (1981). [PMID: 6271231]
  2. Declercq, P.E., Haagsman, H.P., Van Veldhoven, P., Debeer, L.J., Van Golde, L.M.G. and Mannaerts, G.P.
    Rat liver dihydroxyacetone-phosphate acyltransferases and their contribution to glycerolipid synthesis.
    J. Biol. Chem. 259: 9064-9075 (1984).
  3. Hajra, A.K.
    Biosynthesis of acyl dihydroxyacetone phosphate in guinea pig liver mitochondria.
    J. Biol. Chem. 243: 3458-3465 (1968). [PMID: 5656381]

[EC 2.3.1.42 created 1972]