EC 2.1.2.2 - Phosphoribosylglycinamide formyltransferase

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IntEnz Enzyme Nomenclature
EC 2.1.2.2

Names

Accepted name:
phosphoribosylglycinamide formyltransferase
Other names:
2-amino-N-ribosylacetamide 5'-phosphate transformylase
5,10-methenyltetrahydrofolate:2-amino-N-ribosylacetamide ribonucleotide transformylase
GAR TFase
GAR formyltransferase
GAR transformylase
glycinamide ribonucleotide transformylase
Systematic name:
10-formyltetrahydrofolate:5'-phosphoribosylglycinamide N-formyltransferase

Reaction

Links to other databases

Enzymes and pathways: NC-IUBMB , BRENDA , DIAGRAM , ExplorEnz , ENZYME@ExPASy , KEGG , MetaCyc , UniPathway
Protein domains and families: PROSITE:PDOC00319
Structural data: CSA , EC2PDB
Gene Ontology: GO:0004644
CAS Registry Number: 9032-02-4
UniProtKB/Swiss-Prot: (26) [show] [UniProt]

References

  1. Hartman, S.C. and Buchanan, J.M.
    Biosynthesis of the purines. XXVI. The identification of the formyl donors of the transformylation reaction.
    J. Biol. Chem. 234: 1812-1816 (1959). [PMID: 13672969]
  2. Smith, G.K., Benkovic, P.A. and Benkovic, S.J.
    L(-)-10-Formyltetrahydrofolate is the cofactor for glycinamide ribonucleotide transformylase from chicken liver.
    Biochemistry 20: 4034-4036 (1981). [PMID: 7284307]
  3. Warren, L. and Buchanan, J.M.
    Biosynthesis of the purines. XIX. 2-Amino-N-ribosylacetamide 5'-phosphate (glycinamide ribotide) transformylase.
    J. Biol. Chem. 229: 613-626 (1957). [PMID: 13502326]

[EC 2.1.2.2 created 1961, modified 2000]