EC - Tetrahydromethanopterin S-methyltransferase

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IntEnz Enzyme Nomenclature


Accepted name:
tetrahydromethanopterin S-methyltransferase
Other name:
tetrahydromethanopterin methyltransferase
Systematic name:
5-methyl-5,6,7,8-tetrahydromethanopterin:2-mercaptoethanesulfonate 2-methyltransferase



Involved in the formation of methane from CO in Methanobacterium thermoautotrophicum. Methanopterin is a pterin analogue. The reaction involves the export of one or two sodium ions in Archaea.

Links to other databases

Enzymes and pathways: NC-IUBMB , BRENDA , DIAGRAM , ExplorEnz , ENZYME@ExPASy , KEGG , MetaCyc , UM-BBD , UniPathway
Structural data: CSA , EC2PDB
Gene Ontology: GO:0030269
CAS Registry Number: 103406-60-6
UniProtKB/Swiss-Prot: (93) [show] [UniProt]


  1. Sauer, F.D.
    Tetrahydromethanopterin methyltransferase, a component of the methane synthesizing complex of Methanobacterium thermoautotrophicum.
    Biochem. Biophys. Res. Commun. 136: 542-547 (1986). [PMID: 3085670]

[EC created 1989, modified 2000]