EC 2.1.1.56 - MRNA (guanine-N7-)-methyltransferase

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IntEnz Enzyme Nomenclature
EC 2.1.1.56

Names

Accepted name:
mRNA (guanine-N7-)-methyltransferase
Other names:
guanine-7-methyltransferase
messenger RNA guanine 7-methyltransferase
messenger ribonucleate guanine 7-methyltransferase
S-adenosyl-L-methionine:mRNA (guanine-7-N-)-methyltransferase
Systematic name:
S-adenosyl-L-methionine:mRNA (guanine-N7-)-methyltransferase

Reaction

Comments:

The nucleoside next to the terminal guanosine may be either guanosine or adenosine.

Links to other databases

Enzymes and pathways: NC-IUBMB , BRENDA , ExplorEnz , ENZYME@ExPASy , KEGG , MetaCyc , UniPathway
Structural data: CSA , EC2PDB
Gene Ontology: GO:0004482
CAS Registry Number: 56941-25-4
UniProtKB/Swiss-Prot: (232) [show] [UniProt]

References

  1. Ensinger, M.J., Martin, S.A., Paoletti, E.
    and Moss, B. Modification of the 5'-terminus of mRNA by soluble guanylyl and methyl transferases from vaccinia virus.
    Proc. Natl. Acad. Sci. USA 72: 2525-2529 (1975). [PMID: 1058472]
  2. Groner, Y., Gilbao, E. and Aviv, H.
    Methylation and capping of RNA polymerase II primary transcripts by HeLa nuclear homogenates.
    Biochemistry 17: 977-982 (1978). [PMID: 629955]
  3. Martin, S.A. and Moss, B.
    Modification of RNA by mRNA guanylyltransferase and mRNA (guanine-7)methyltransferase from vaccinia virions.
    J. Biol. Chem. 250: 9330-9335 (1975). [PMID: 1194287]
  4. Martin, S.A., Paoletti, E. and Moss, B.
    Purification of mRNA guanylyltransferase and mRNA (guanine-7-) methyltransferase from vaccinia virions.
    J. Biol. Chem. 250: 9322-9329 (1975). [PMID: 1194286]

[EC 2.1.1.56 created 1981]