EC 2.1.1.28 - Phenylethanolamine N-methyltransferase

  IntEnz view ENZYME view

IntEnz Enzyme Nomenclature
EC 2.1.1.28

Names

Accepted name:
phenylethanolamine N-methyltransferase
Other names:
noradrenalin N-methyltransferase
noradrenaline N-methyltransferase
norepinephrine N-methyltransferase
norepinephrine methyltransferase
phenethanolamine N-methyltransferase
phenethanolamine methyltransferase
Systematic name:
S-adenosyl-L-methionine:phenylethanolamine N-methyltransferase

Reactions

Comments:

Acts on various phenylethanolamines; converts noradrenaline into adrenaline.

Links to other databases

Enzymes and pathways: NC-IUBMB , BRENDA , DIAGRAM , ExplorEnz , ENZYME@ExPASy , KEGG , MetaCyc , UniPathway
Protein domains and families: PROSITE:PDOC00844
Structural data: CSA , EC2PDB
Gene Ontology: GO:0004603
CAS Registry Number: 9037-68-7
UniProtKB/Swiss-Prot: (43) [show] [UniProt]

References

  1. Axelrod, J.
    Purification and properties of phenylethanolamine-N-methyl transferase.
    J. Biol. Chem. 237: 1657-1660 (1962).
  2. Connett, R.J. and Kirschner, N.
    Purification and properties of bovine phenylethanolamine N-methyltransferase.
    J. Biol. Chem. 245: 329-334 (1970). [PMID: 5412063]

[EC 2.1.1.28 created 1972]