EC 2.1.1.181 - 23S rRNA (adenine1618-N6)-methyltransferase

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IntEnz Enzyme Nomenclature
EC 2.1.1.181

Names

Accepted name:
23S rRNA (adenine1618-N6)-methyltransferase
Other names:
rRNA large subunit methyltransferase F
YbiN protein
rlmF
m6A1618
Systematic name:
S-adenosyl-L-methionine:(adenine1618-N6)-methyltransferase

Reaction

Comments:

The recombinant YbiN protein is able to methylate partially deproteinized 50 S ribosomal subunit, but neither the completely assembled 50 S subunits nor completely deproteinized 23 S rRNA [1].

Links to other databases

Enzymes and pathways: NC-IUBMB , BRENDA , ExplorEnz , ENZYME@ExPASy , KEGG , MetaCyc , UniPathway
Protein domains and families: PROSITE:PDOC00871
Structural data: CSA , EC2PDB
Gene Ontology: GO:0052907
CAS Registry Number: 9076-81-7
UniProtKB/Swiss-Prot: (124) [show] [UniProt]

References

  1. Sergiev, P.V., Serebryakova, M.V., Bogdanov, A.A. and Dontsova, O.A.
    The ybiN gene of Escherichia coli encodes adenine-N6 methyltransferase specific for modification of A1618 of 23 S ribosomal RNA, a methylated residue located close to the ribosomal exit tunnel.
    J. Mol. Biol. 375: 291-300 (2008). [PMID: 18021804]

[EC 2.1.1.181 created 1976 as EC 2.1.1.48, part-transferred 2010 to EC 2.1.1.181]