EC 2.1.1.176 - 16S rRNA (cytosine967-C5)-methyltransferase

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IntEnz Enzyme Nomenclature
EC 2.1.1.176

Names

Accepted name:
16S rRNA (cytosine967-C5)-methyltransferase
Other names:
rsmB
fmu
16S rRNA m5C967 methyltransferase
Systematic name:
S-adenosyl-L-methionine:16S rRNA (cytosine967-C5)-methyltransferase

Reaction

Comments:

The enzyme specifically methylates cytosine967 at C5 in 16S rRNA.

Links to other databases

Enzymes and pathways: NC-IUBMB , BRENDA , ExplorEnz , ENZYME@ExPASy , KEGG , MetaCyc , UniPathway
Structural data: CSA , EC2PDB
UniProtKB/Swiss-Prot: (84) [show] [UniProt]

References

  1. Tscherne, J. S., Nurse, K., Popienick, P., Michel, H., Sochacki, M., Ofengand, J.
    Purification, cloning, and characterization of the 16S RNA m5C967 methyltransferase from Escherichia coli.
    Biochemistry 38: 1884-1892 (1999). [PMID: 10026269]
  2. Gu, X. R., Gustafsson, C., Ku, J., Yu, M., Santi, D. V.
    Identification of the 16S rRNA m5C967 methyltransferase from Escherichia coli.
    Biochemistry 38: 4053-4057 (1999). [PMID: 10194318]
  3. Foster, P. G., Nunes, C. R., Greene, P., Moustakas, D., Stroud, R. M.
    The first structure of an RNA m5C methyltransferase, Fmu, provides insight into catalytic mechanism and specific binding of RNA substrate.
    Structure 11: 1609-1620 (2003). [PMID: 14656444]

[EC 2.1.1.176 created 2010]