EC 2.1.1.174 - 23S rRNA (guanine1835-N2)-methyltransferase

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IntEnz Enzyme Nomenclature
EC 2.1.1.174

Names

Accepted name:
23S rRNA (guanine1835-N2)-methyltransferase
Other names:
ygjO
rlmG
ribosomal RNA large subunit methyltransferase G
Systematic name:
S-adenosyl-L-methionine:23S rRNA (guanine1835-N2)-methyltransferase

Reaction

Comments:

The enzyme methylates 23S rRNA in vitro, assembled 50S subunits are not a substrate [1]. The enzyme specifically methylates guanine1835 at N2 in 23S rRNA.

Links to other databases

Enzymes and pathways: NC-IUBMB , BRENDA , ExplorEnz , ENZYME@ExPASy , KEGG , MetaCyc , UniPathway
Structural data: CSA , EC2PDB
Gene Ontology: GO:0052916
UniProtKB/Swiss-Prot: (106) [show] [UniProt]

References

  1. Sergiev, P. V., Lesnyak, D. V., Bogdanov, A. A., Dontsova, O. A.
    Identification of Escherichia coli m2G methyltransferases: II. The ygjO gene encodes a methyltransferase specific for G1835 of the 23 S rRNA.
    J. Mol. Biol. 364: 26-31 (2006). [PMID: 17010380]

[EC 2.1.1.174 created 1976 as EC 2.1.1.52, part-transferred 2010 to EC 2.1.1.174]