EC 2.1.1.171 - 16S rRNA (guanine966-N2)-methyltransferase

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IntEnz Enzyme Nomenclature
EC 2.1.1.171

Names

Accepted name:
16S rRNA (guanine966-N2)-methyltransferase
Other names:
yhhF
rsmD
m2G966 methyltransferase
Systematic name:
S-adenosyl-L-methionine:16S rRNA (guanine966-N2)-methyltransferase

Reaction

Comments:

The enzyme efficiently methylates guanine966 of the assembled 30S subunits in vitro. Protein-free 16S rRNA is not a substrate for RsmD [1]. The enzyme specifically methylates guanine966 at N2 in 16S rRNA.

Links to other databases

Enzymes and pathways: NC-IUBMB , BRENDA , ExplorEnz , ENZYME@ExPASy , KEGG , MetaCyc , UniPathway
Structural data: CSA , EC2PDB
Gene Ontology: GO:0052913
UniProtKB/Swiss-Prot:

References

  1. Lesnyak, D. V., Osipiuk, J., Skarina, T., Sergiev, P. V., Bogdanov, A. A., Edwards, A., Savchenko, A., Joachimiak, A., Dontsova, O. A.
    Methyltransferase that modifies guanine 966 of the 16 S rRNA: functional identification and tertiary structure.
    J. Biol. Chem. 282: 5880-5887 (2007). [PMID: 17189261]

[EC 2.1.1.171 created 1976 as EC 2.1.1.52, part-transferred 2010 to EC 2.1.1.171]