EC 2.1.1.170 - 16S rRNA (guanine527-N7)-methyltransferase

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IntEnz Enzyme Nomenclature
EC 2.1.1.170

Names

Accepted name:
16S rRNA (guanine527-N7)-methyltransferase
Other names:
ribosomal RNA small subunit methyltransferase G
16S rRNA methyltransferase RsmG
GidB
rsmG
Systematic name:
S-adenosyl-L-methionine:16S rRNA (guanine527-N7)-methyltransferase

Reaction

Comments:

The enzyme specifically methylates guanine527 at N7 in 16S rRNA.

Links to other databases

Enzymes and pathways: NC-IUBMB , BRENDA , ExplorEnz , ENZYME@ExPASy , KEGG , MetaCyc , UniPathway
Structural data: CSA , EC2PDB
UniProtKB/Swiss-Prot: (368) [show] [UniProt]

References

  1. Okamoto, S., Tamaru, A., Nakajima, C., Nishimura, K., Tanaka, Y., Tokuyama, S., Suzuki, Y., Ochi, K.
    Loss of a conserved 7-methylguanosine modification in 16S rRNA confers low-level streptomycin resistance in bacteria.
    Mol. Microbiol. 63: 1096-1106 (2007). [PMID: 17238915]
  2. Romanowski, M. J., Bonanno, J. B., Burley, S. K.
    Crystal structure of the Escherichia coli glucose-inhibited division protein B (GidB) reveals a methyltransferase fold.
    Proteins 47: 563-567 (2002). [PMID: 12001236]

[EC 2.1.1.170 created 2010]