EC 1.7.2.2 - Nitrite reductase (cytochrome; ammonia-forming)

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IntEnz Enzyme Nomenclature
EC 1.7.2.2

Names

Accepted name:
nitrite reductase (cytochrome; ammonia-forming)
Other names:
cytochrome c nitrite reductase
multiheme nitrite reductase
Systematic name:
ammonia:ferricytochrome-c oxidoreductase

Reaction

Cofactors

Comments:

Found as a multiheme cytochrome in many bacteria. The enzyme from Escherichia coli contains five hemes c and requires Ca2+. It also reduces nitric oxide and hydroxylamine to ammonia, and sulfite to sulfide.

Links to other databases

Enzymes and pathways: NC-IUBMB , BRENDA , ExplorEnz , ENZYME@ExPASy , KEGG , MetaCyc , UniPathway
Structural data: CSA , EC2PDB
Gene Ontology: GO:0042279
UniProtKB/Swiss-Prot: (78) [show] [UniProt]

References

  1. Einsle, O., Messerschmidt, A., Stach, P. Bourenkov, G.P., Bartunik, H.D., Huber, R. and Kroneck, P.M.H.
    Structure of cytochrome c nitrite reductase.
    Nature 400: 476-480 (1999). [PMID: 10440380]

[EC 1.7.2.2 created 2001]