EC 1.6.1.1 - NAD(P)+ transhydrogenase (Si-specific)

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IntEnz Enzyme Nomenclature
EC 1.6.1.1

Names

Accepted name:
NAD(P)+ transhydrogenase (Si-specific)
Other names:
H+-Thase
NAD transhydrogenase
NAD(P) transhydrogenase
NADH transhydrogenase
NADH-NADP-transhydrogenase
NADPH-NAD oxidoreductase
NADPH-NAD transhydrogenase
NADPH:NAD+ transhydrogenase
nicotinamide adenine dinucleotide (phosphate) transhydrogenase
nicotinamide nucleotide transhydrogenase
non-energy-linked transhydrogenase
pyridine nucleotide transferase
pyridine nucleotide transhydrogenase
transhydrogenase
NAD(P)+ transhydrogenase (B-specific)
NADPH:NAD+ oxidoreductase (B-specific)
Systematic name:
NADPH:NAD+ oxidoreductase (Si-specific)

Reaction

Cofactor

Comments:

The enzyme from Azotobacter vinelandii is a flavoprotein (FAD). It is Si-specific with respect to both NAD+ and NADP+. Also acts on deamino coenzymes (cf. EC 1.6.1.2 NAD(P)+ transhydrogenase (Re/Si-specific)).

Links to other databases

Enzymes and pathways: NC-IUBMB , BRENDA , ExplorEnz , ENZYME@ExPASy , KEGG , MetaCyc , NIST 74 , UniPathway
Protein domains and families: PROSITE:PDOC00073
Structural data: CSA , EC2PDB
Gene Ontology: GO:0003957
CAS Registry Numbers: 9014-18-0 9072-60-0
UniProtKB/Swiss-Prot: (95) [show] [UniProt]

References

  1. Humphrey, G.F.
    The distribution and properties of transhydrogenase from animal tissues.
    Biochem. J. 65: 546-550 (1957). [PMID: 13412660]
  2. You, K.-S.
    Stereospecificity for nicotinamide nucleotides in enzymatic and chemical hydride transfer reactions.
    CRC Crit. Rev. Biochem. 17: 313-451 (1985). [PMID: 85178338]

[EC 1.6.1.1 created 1961, modified 1986, modified 2013]