EC 1.5.99.6 - Spermidine dehydrogenase

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IntEnz Enzyme Nomenclature
EC 1.5.99.6

Names

Accepted name:
spermidine dehydrogenase
Other name:
spermidine:(acceptor) oxidoreductase
Systematic name:
spermidine:acceptor oxidoreductase

Reactions

Cofactors

Comments:

A flavohemoprotein (FAD). Ferricyanide, 2,6-dichloroindophenol and cytochrome c can act as acceptor. 4-Aminobutanal condenses non-enzymically to 1-pyrroline.

Links to other databases

Enzymes and pathways: NC-IUBMB , BRENDA , ExplorEnz , ENZYME@ExPASy , KEGG , MetaCyc , UniPathway
Structural data: CSA , EC2PDB
Gene Ontology: GO:0050289
CAS Registry Number: 9076-64-6

References

  1. Tabor, C.W. and Kellogg, P.D.
    Identification of flavin adenine dinucleotide and heme in a homogeneous spermidine dehydrogenase from Serratia marcescens.
    J. Biol. Chem. 245: 5424-5433 (1970).
  2. Tabor, H. and Tabor, C.W.
    Biosynthesis and metabolism of 1,4-diaminobutane, spermidine, spermine, and related amines. IIE2a Speridine dehydrogenase.
    Adv. Enzymol. Relat. Areas Mol. Biol. 36: 225-226 (1972).

[EC 1.5.99.6 created 1976]