EC 1.5.3.14 - Polyamine oxidase (propane-1,3-diamine-forming)

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IntEnz Enzyme Nomenclature
EC 1.5.3.14

Names

Accepted name:
polyamine oxidase (propane-1,3-diamine-forming)
Other name:
MPAO
Systematic name:
spermidine:oxygen oxidoreductase (propane-1,3-diamine-forming)

Reactions

Cofactor

Comments:

As the products of the reaction cannot be converted directly to other polyamines, this class of polyamine oxidases is considered to be involved in the terminal catabolism of polyamines [1]. This enzyme less efficiently catalyses the oxidation of N1-acetylspermine and spermine. A flavoprotein (FAD). Differs in specificity from EC 1.5.3.13 (N1-acetylpolyamine oxidase), EC 1.5.3.15 (N8-acetylspermidine oxidase (propane-1,3-diamine-forming)), EC 1.5.3.16 (spermine oxidase) and EC 1.5.3.17 (non-specific polyamine oxidase).

Links to other databases

Enzymes and pathways: NC-IUBMB , BRENDA , ExplorEnz , ENZYME@ExPASy , KEGG , MetaCyc , UniPathway
Structural data: CSA , EC2PDB
Gene Ontology: GO:0052893 , GO:0052896 , GO:0052900
UniProtKB/Swiss-Prot:

References

  1. Tavladoraki, P., Schinina, M. E., Cecconi, F., Di Agostino, S., Manera, F., Rea, G., Mariottini, P., Federico, R., Angelini, R.
    Maize polyamine oxidase: primary structure from protein and cDNA sequencing.
    FEBS Lett. 426: 62-66 (1998). [PMID: 9598979]
  2. Federico, R., Ercolini, L., Laurenzi, M., Angelini, R.
    Oxidation of acetylpolyamines by maize polyamine oxidase.
    Phytochemistry 43: 339-341 (1996).

[EC 1.5.3.14 created 2009]