EC 1.4.3.19 - Glycine oxidase

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IntEnz Enzyme Nomenclature
EC 1.4.3.19

Names

Accepted name:
glycine oxidase
Systematic name:
glycine:oxygen oxidoreductase (deaminating)

Reactions

Cofactor

Comments:

A flavoenzyme containing non-covalently bound FAD. The enzyme from Bacillus subtilis is active with glycine, sarcosine, N-ethylglycine, D-alanine, D-α-aminobutyrate, D-proline, D-pipecolate and N-methyl-D-alanine. It differs from EC 1.4.3.3, D-amino acid oxidase, due to its activity on sarcosine and D-pipecolate. The intermediate 2-iminoacetate is used directly by EC 2.8.1.10, thiazole synthase.

Links to other databases

Enzymes and pathways: NC-IUBMB , BRENDA , DIAGRAM , ExplorEnz , ENZYME@ExPASy , KEGG , MetaCyc , UniPathway
Structural data: CSA , EC2PDB
Gene Ontology: GO:0043799
CAS Registry Number: 39307-16-9
UniProtKB/Swiss-Prot:

References

  1. Job, V., Marcone, G.L., Pilone, M.S. and Pollegioni, L.
    Glycine oxidase from Bacillus subtilis. Characterization of a new flavoprotein.
    J. Biol. Chem. 277: 6985-6993 (2002). [PMID: 11744710]
  2. Nishiya, Y. and Imanaka, T.
    Purification and characterization of a novel glycine oxidase from Bacillus subtilis.
    FEBS Lett. 438: 263-266 (1998). [PMID: 9827558]

[EC 1.4.3.19 created 2002, modified 2012]