EC 1.3.1.72 - Δ24-sterol reductase

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IntEnz Enzyme Nomenclature
EC 1.3.1.72

Names

Accepted name:
Δ24-sterol reductase
Other name:
lanosterol Δ24-reductase
Systematic name:
sterol:NADP+ Δ24-oxidoreductase

Reactions

Comments:

Acts on a range of steroids with a 24(25)-double bond, including lanosterol, desmosterol and zymosterol.

Links to other databases

Enzymes and pathways: NC-IUBMB , BRENDA , DIAGRAM , ExplorEnz , ENZYME@ExPASy , KEGG , MetaCyc , UniPathway
Structural data: CSA , EC2PDB
Gene Ontology: GO:0050614
CAS Registry Number: 9033-57-2
UniProtKB/Swiss-Prot:

References

  1. Bae, S.H. and Paik, Y.K.
    Cholesterol biosynthesis from lanosterol: development of a novel assay method and characterization of rat liver microsomal lanosterol Δ24-reductase.
    Biochem. J. 326: 609-616 (1997). [PMID: 9291139]

[EC 1.3.1.72 created 2001]