EC 1.3.1.10 - Enoyl-[acyl-carrier-protein] reductase (NADPH, Si-specific)

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IntEnz Enzyme Nomenclature
EC 1.3.1.10

Names

Accepted name:
enoyl-[acyl-carrier-protein] reductase (NADPH, Si-specific)
Other names:
NADPH 2-enoyl Co A reductase
acyl-ACP dehydrogenase [ambiguous]
enoyl acyl-carrier-protein reductase [ambiguous]
enoyl-ACP reductase [ambiguous]
enoyl-[acyl carrier protein] (reduced nicotinamide adenine dinucleotide phosphate) reductase
enoyl-[acyl-carrier-protein] reductase (NADPH, B-specific)
acyl-[acyl-carrier-protein]:NADP+ oxidoreductase (B-specific)
acyl-[acyl-carrier protein]:NADP+ oxidoreductase (B-specific)
Systematic name:
acyl-[acyl-carrier-protein]:NADP+ oxidoreductase (Si-specific)

Reaction

Comments:

One of the activities of EC 2.3.1.86, fatty-acyl-CoA synthase, an enzyme found in yeasts (Ascomycota and the Basidiomycota). Catalyses the reduction of enoyl-acyl-[acyl-carrier protein] derivatives of carbon chain length from 4 to 16. The yeast enzyme is Si-specific with respect to NADP+. cf. EC 1.3.1.39, enoyl-[acyl-carrier-protein] reductase (NADPH, Re-specific) and EC 1.3.1.104, enoyl-[acyl-carrier-protein] reductase (NADPH), which describes enzymes whose stereo-specificity towards NADPH is not known. See also EC 1.3.1.9, enoyl-[acyl-carrier-protein] reductase (NADH).

Links to other databases

Enzymes and pathways: NC-IUBMB , BRENDA , ExplorEnz , ENZYME@ExPASy , KEGG , MetaCyc , UniPathway
Structural data: CSA , EC2PDB
Gene Ontology: GO:0004319
CAS Registry Number: 37251-09-5

References

  1. Seyama, T., Kasama, T., Yamakawa, T., Kawaguchi, A., Saito, K. and Okuda, S.
    Origin of hydrogen atoms in the fatty acids synthesized with yeast fatty acid synthetase.
    J. Biochem. (Tokyo) 82: 1325-1329 (1977). [PMID: 338601]

[EC 1.3.1.10 created 1972, modified 1986, modified 2013, modified 2014]