EC 1.2.1.58 - Phenylglyoxylate dehydrogenase (acylating)

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IntEnz Enzyme Nomenclature
EC 1.2.1.58

Names

Accepted name:
phenylglyoxylate dehydrogenase (acylating)
Systematic name:
phenylglyoxylate:NAD+ oxidoreductase

Reaction

Cofactors

Comments:

Requires thiamine diphosphate as cofactor. The enzyme from the denitrifying bacterium Azoarcus evansii is specific for phenylglyoxylate. 2-Oxoisovalerate is oxidized at 15% of the rate for phenylglyoxylate. Also reduces viologen dyes. Contains iron-sulfur centres and FAD.

Links to other databases

Enzymes and pathways: NC-IUBMB , BRENDA , ExplorEnz , ENZYME@ExPASy , KEGG , MetaCyc , UniPathway
Structural data: CSA , EC2PDB
Gene Ontology: GO:0047110
CAS Registry Number: 205510-78-7
UniProtKB/Swiss-Prot:

References

  1. Hirsch, W., Schägger, H. and Fuchs, G.
    Phenylglyoxylate:NAD+ oxidoreductase (CoA benzoylating), a new enzyme of anaerobic phenylalanine metabolism in the denitrifying bacterium Axoarcus evansii.
    Eur. J. Biochem. 251: 907-915 (1998). [PMID: 9490067]

[EC 1.2.1.58 created 1999]