EC 1.2.1.51 - Pyruvate dehydrogenase (NADP+)

  IntEnz view ENZYME view

IntEnz Enzyme Nomenclature
EC 1.2.1.51

Names

Accepted name:
pyruvate dehydrogenase (NADP+)
Systematic name:
pyruvate:NADP+ 2-oxidoreductase (CoA-acetylating)

Reaction

Comments:

The Euglena enzyme can also use FAD or methylviologen as acceptor, more slowly. The enzyme is inhibited by oxygen.

Links to other databases

Enzymes and pathways: NC-IUBMB , BRENDA , ExplorEnz , ENZYME@ExPASy , KEGG , MetaCyc , UniPathway
Structural data: CSA , EC2PDB
Gene Ontology: GO:0050243
CAS Registry Number: 93389-35-6
UniProtKB/Swiss-Prot:

References

  1. Inui, H., Miyatake, K., Nakano, Y. and Kitaoka, S.
    Occurrence of oxygen-sensitive, NADP+-dependent pyruvate dehydrogenase in mitochondria of Euglena gracilis.
    J. Biochem. (Tokyo) 96: 931-934 (1984). [PMID: 6438078]
  2. Inui, H., Ono, K., Miyatake, K., Nakano, Y. and Kitaoka, S.
    Purification and characterization of pyruvate:NADP+ oxidoreductase in Euglena gracilis.
    J. Biol. Chem. 262: 9130-9135 (1987). [PMID: 3110154]

[EC 1.2.1.51 created 1989]