EC - Cinnamoyl-CoA reductase

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IntEnz Enzyme Nomenclature


Accepted name:
cinnamoyl-CoA reductase
Other names:
p-hydroxycinnamoyl coenzyme A reductase
cinnamoyl-CoA:NADPH reductase
cinnamoyl-coenzyme A reductase
feruloyl coenzyme A reductase
feruloyl-CoA reductase
ferulyl-CoA reductase
Systematic name:
cinnamaldehyde:NADP+ oxidoreductase (CoA-cinnamoylating)



Acts also on a number of substituted cinnamoyl esters of coenzyme A.

Links to other databases

Enzymes and pathways: NC-IUBMB , BRENDA , ERGO , ExplorEnz , ENZYME@ExPASy , KEGG , MetaCyc , UniPathway
Structural data: CSA , EC2PDB
Gene Ontology: GO:0016621
CAS Registry Number: 59929-39-4


  1. Gross, G.G. and Kreiten, W.
    Reduction of coenzyme A thioesters of cinnamic acids with an enzyme preparation from lignifying tissue of Forsythia.
    FEBS Lett. 54: 259-262 (1975). [PMID: 236926]
  2. Sarni, F., Grand, C. and Baudet, A.M.
    Purification and properties of cinnamoyl-CoA reductase and cinnamyl alcohol dehydrogenase from poplar stems (Populus X euramericana).
    Eur. J. Biochem. 139: 259-265 (1984). [PMID: 6365550]
  3. Wengenmayer, H., Ebel, J. and Grisebach, H.
    Enzymic synthesis of lignin precursors. Purification and properties of a cinnamoyl-CoA: NADPH reductase from cell suspension cultures of soybean (Glycinemax).
    Eur. J. Biochem. 65: 529-536 (1976). [PMID: 7454]

[EC created 1978]