EC 1.14.15.1 - Camphor 5-monooxygenase

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IntEnz Enzyme Nomenclature
EC 1.14.15.1

Names

Accepted name:
camphor 5-monooxygenase
Other names:
2-bornanone 5-exo-hydroxylase
D-camphor-exo-hydroxylase
bornanone 5-exo-hydroxylase
camphor 5-exo-hydroxylase
camphor 5-exo-methylene hydroxylase
camphor 5-exohydroxylase
camphor hydroxylase
camphor methylene hydroxylase
d-camphor monooxygenase
methylene hydroxylase
methylene monooxygenase
Systematic name:
(+)-camphor,reduced putidaredoxin:oxygen oxidoreductase (5-hydroxylating)

Reaction

Cofactor

Comments:

A heme-thiolate protein (P-450). Also acts on (−)-camphor and 1,2-campholide, forming 5-exo-hydroxy-1,2-campholide.

Links to other databases

Enzymes and pathways: NC-IUBMB , BRENDA , ExplorEnz , ENZYME@ExPASy , KEGG , MetaCyc , UM-BBD , UniPathway
Protein domains and families: PROSITE:PDOC00081
Structural data: CSA , EC2PDB
Gene Ontology: GO:0018683
CAS Registry Number: 9030-82-4
UniProtKB/Swiss-Prot:

References

  1. Hedegaard, J. and Gunsalus, I.C.
    Mixed function oxidation. IV. An induced methylene hydroxylase in camphor oxidation.
    J. Biol. Chem. 240: 4038-4043 (1965). [PMID: 4378858]
  2. Tyson, C.A., Lipscomb, J.D. and Gunsalus, I.C.
    The role of putidaredoxin and P450 cam in methylene hydroxylation.
    J. Biol. Chem. 247: 5777-5784 (1972). [PMID: 4341491]

[EC 1.14.15.1 created 1972, modified 1986]