EC 1.14.13.71 - N-methylcoclaurine 3'-monooxygenase

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IntEnz Enzyme Nomenclature
EC 1.14.13.71

Names

Accepted name:
N-methylcoclaurine 3'-monooxygenase
Other name:
N-methylcoclaurine 3'-hydroxylase
Systematic name:
(S)-N-methylcoclaurine,NADPH:oxygen oxidoreductase (3'-hydroxylating)

Reaction

Cofactor

Comments:

A heme-thiolate protein (P-450) involved in benzylisoquinoline alkaloid synthesis in higher plants.

Links to other databases

Enzymes and pathways: NC-IUBMB , BRENDA , DIAGRAM , ExplorEnz , ENZYME@ExPASy , KEGG , MetaCyc , UniPathway
Protein domains and families: PROSITE:PDOC00081
Structural data: CSA , EC2PDB
Gene Ontology: GO:0050593
UniProtKB/Swiss-Prot:

References

  1. Pauli, H.H. and Kutchan, T.M.
    Molecular cloning and functional heterologous expression of two alleles encoding (S)-N-methylcoclaurine 3'-hydroxylase (CYP80B1), a new methyl jasmonate-inducible cytochrome P-450-dependent mono-oxygenase of benzylisoquinoline alkaloid biosynthesis.
    Plant. J. 13: 793-801 (1998). [PMID: 9681018]

[EC 1.14.13.71 created 2001]