EC 1.14.12.4 - 3-hydroxy-2-methylpyridinecarboxylate dioxygenase

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IntEnz Enzyme Nomenclature
EC 1.14.12.4

Names

Accepted name:
3-hydroxy-2-methylpyridinecarboxylate dioxygenase
Other names:
2-methyl-3-hydroxypyridine 5-carboxylic acid dioxygenase
3-hydroxy-3-methylpyridinecarboxylate dioxygenase [incorrect]
methylhydroxypyridine carboxylate dioxygenase
methylhydroxypyridinecarboxylate oxidase
3-hydroxy-2-methylpyridine-5-carboxylate,NAD(P)H:oxygen oxidoreductase (decyclizing)
Systematic name:
3-hydroxy-2-methylpyridine-5-carboxylate,NAD(P)H:oxygen oxidoreductase (ring-opening)

Reactions

Cofactor

Comments:

A flavoprotein (FAD).

Links to other databases

Enzymes and pathways: NC-IUBMB , BRENDA , ERGO , ExplorEnz , ENZYME@ExPASy , KEGG , MetaCyc , UniPathway
Structural data: CSA , EC2PDB
Gene Ontology: GO:0047081
CAS Registry Number: 37256-69-2

References

  1. Sparrow, L.G., Ho, P.P.K., Sundaram, T.K., Zach, D., Nyns, E.J. and Snell, E.E.
    The bacterial oxidation of vitamin B6. VII. Purification, properties, and mechanism of action of an oxygenase which cleaves the 3-hydroxypyridine ring.
    J. Biol. Chem. 244: 2590-2600 (1969). [PMID: 4306031]

[EC 1.14.12.4 created 1972]