EC 1.13.11.4 - Gentisate 1,2-dioxygenase

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IntEnz Enzyme Nomenclature
EC 1.13.11.4

Names

Accepted name:
gentisate 1,2-dioxygenase
Other names:
2,5-dihydroxybenzoate dioxygenase
gentisate dioxygenase
gentisate oxygenase
gentisic acid oxidase
gentisate:oxygen 1,2-oxidoreductase (decyclizing)
Systematic name:
gentisate:oxygen 1,2-oxidoreductase (ring-opening)

Reaction

Cofactor

Comments:

Requires Fe2+. Formerly EC 1.13.1.4 and 1.99.2.4.

Links to other databases

Enzymes and pathways: NC-IUBMB , BRENDA , ExplorEnz , ENZYME@ExPASy , KEGG , MetaCyc , UniPathway
Structural data: CSA , EC2PDB
Gene Ontology: GO:0047922
CAS Registry Number: 9029-48-5
UniProtKB/Swiss-Prot:

References

  1. Hayaishi, O.
    Direct oxygenation by O2, oxygenases.
    In: Boyer, P.D., Lardy, H. and Myrbäck, K. (Eds.) The Enzymes, 2nd ed. vol. 8, Academic Press, New York, 1963, 353-371
  2. Sugiyama, S., Yano, K., Komagata, K. and Arima, K.
    Metabolites of aromatic compounds by microbes. Part VII. Gentisic acid oxidase.
    Bull. Agric. Chem. Soc. Jpn 24: 243-248 (1960).
  3. Sugiyama, S., Yano, K. and Arima, K.
    Metabolites of aromatic compounds by microbes. Part VII. Further studies of gentisic acid oxidase.
    Bull. Agric. Chem. Soc. Jpn 24: 249-254 (1960).

[EC 1.13.11.4 created 1961 as EC 1.99.2.4, transferred 1965 to EC 1.13.1.4, transferred 1972 to EC 1.13.11.4]