EC 1.13.11.37 - Hydroxyquinol 1,2-dioxygenase

  IntEnz view ENZYME view

IntEnz Enzyme Nomenclature
EC 1.13.11.37

Names

Accepted name:
hydroxyquinol 1,2-dioxygenase
Other names:
hydroxyquinol dioxygenase
benzene-1,2,4-triol:oxygen 1,2-oxidoreductase (ring-opening)
Systematic name:
benzene-1,2,4-triol:oxygen 1,2-oxidoreductase (decyclizing)

Reaction

Cofactor

Comments:

An iron protein. Highly specific; catechol and pyrogallol are acted on at less than 1% of the rate at which hydroxyquinol is oxidized.

Links to other databases

Enzymes and pathways: NC-IUBMB , BRENDA , DIAGRAM , ExplorEnz , ENZYME@ExPASy , KEGG , MetaCyc , UM-BBD , UniPathway
Structural data: CSA , EC2PDB
Gene Ontology: GO:0018581
CAS Registry Number: 91847-14-2
UniProtKB/Swiss-Prot:

References

  1. Sze, I.S.-Y. and Dagley, S.
    Properties of salicylate hydroxylase and hydroxyquinol 1,2-dioxygenase purified from Trichosporon cutaneum.
    J. Bacteriol. 159: 353-359 (1984). [PMID: 6539772]
  2. Ferraroni, M., Seifert, J., Travkin, V. M., Thiel, M., Kaschabek, S., Scozzafava, A., Golovleva, L., Schlomann, M., Briganti, F.
    Crystal structure of the hydroxyquinol 1,2-dioxygenase from Nocardioides simplex 3E, a key enzyme involved in polychlorinated aromatics biodegradation.
    J. Biol. Chem. 280: 21144-21154 (2005). [PMID: 15772073]
  3. Hatta, T., Nakano, O., Imai, N., Takizawa, N., Kiyohara, H.
    Cloning and sequence analysis of hydroxyquinol 1,2-dioxygenase gene in 2,4,6-trichlorophenol-degrading Ralstonia pickettii DTP0602 and characterization of its product.
    J. Biosci. Bioeng. 87: 267-272 (1999). [PMID: 16232466]

[EC 1.13.11.37 created 1989, modified 2013]