EC 1.13.11.25 - 3,4-dihydroxy-9,10-secoandrosta-1,3,5(10)-triene-9,17-dione 4,5-dioxygenase

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IntEnz Enzyme Nomenclature
EC 1.13.11.25

Names

Accepted name:
3,4-dihydroxy-9,10-secoandrosta-1,3,5(10)-triene-9,17-dione 4,5-dioxygenase
Other names:
3-alkylcatechol 2,3-dioxygenase
steroid 4,5-dioxygenase
3,4-dihydroxy-9,10-secoandrosta-1,3,5(10)-triene-9,17-dione:oxygen 4,5-oxidoreductase (decyclizing)
Systematic name:
3,4-dihydroxy-9,10-secoandrosta-1,3,5(10)-triene-9,17-dione:oxygen 4,5-oxidoreductase (ring-opening)

Reaction

Cofactor

Comments:

Requires Fe2+. Also acts on 3-isopropylcatechol and 3-tert-butyl-5-methylcatechol.

Links to other databases

Enzymes and pathways: NC-IUBMB , BRENDA , ExplorEnz , ENZYME@ExPASy , KEGG , MetaCyc , UniPathway
Structural data: CSA , EC2PDB
Gene Ontology: GO:0047071
CAS Registry Number: 37256-63-6
UniProtKB/Swiss-Prot:

References

  1. Gibson, D.T., Wang, K.C., Sih, C.J. and Whitlock, J.H.
    Mechanisms of steroid oxidation by microorganisms. IX. On the mechanism of ring A cleavage in the degradation of 9,10-seco steroids by microorganisms.
    J. Biol. Chem. 241: 551-559 (1966). [PMID: 5908121]

[EC 1.13.11.25 created 1972]