EC 1.13.11.16 - 3-carboxyethylcatechol 2,3-dioxygenase

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IntEnz Enzyme Nomenclature
EC 1.13.11.16

Names

Accepted name:
3-carboxyethylcatechol 2,3-dioxygenase
Other names:
2,3-dihydroxy-β-phenylpropionate oxygenase
2,3-dihydroxy-β-phenylpropionic dioxygenase
3-(2,3-dihydroxyphenyl)propanoate:oxygen 1,2-oxidoreductase
3-(2,3-dihydroxyphenyl)propanoate:oxygen 1,2-oxidoreductase (decyclizing)
Systematic name:
3-(2,3-dihydroxyphenyl)propanoate:oxygen 1,2-oxidoreductase (ring-opening)

Reactions

Cofactor

Comments:

An iron protein. This enzyme catalyses a step in the pathway of phenylpropanoid compounds degradation.

Links to other databases

Enzymes and pathways: NC-IUBMB , BRENDA , DIAGRAM , DIAGRAM , ExplorEnz , ENZYME@ExPASy , KEGG , MetaCyc , UniPathway
Structural data: CSA , EC2PDB
Gene Ontology: GO:0047070
CAS Registry Number: 105503-63-7
UniProtKB/Swiss-Prot: (42) [show] [UniProt]

References

  1. Dagley, S., Chapman, P.J. and Gibson, D.T.
    The metabolism of β-phenylpropionic acid by an Achromobacter.
    Biochem. J. 97: 643-650 (1965). [PMID: 5881653]
  2. Lam, W. W. Y and Bugg, T. D. H.
    Chemistry of extradiol aromatic ring cleavage: isolation of a stable dienol ring fission intermediate and stereochemistry of its enzymatic hydrolytic clevage.
    J. Chem. Soc., Chem. Commun. 10: 1163-1164 (1994).
  3. Diaz, E., Ferrandez, A., Garcia, J. L.
    Characterization of the hca cluster encoding the dioxygenolytic pathway for initial catabolism of 3-phenylpropionic acid in Escherichia coli K-12.
    J. Bacteriol. 180: 2915-2923 (1998). [PMID: 9603882]

[EC 1.13.11.16 created 1972, modified 2011, modified 2012]