IntEnz

EC 1.13.11.1 - Catechol 1,2-dioxygenase

IntEnz Enzyme Nomenclature
EC 1.13.11.1

Names

Reaction

• 23852 [IUBMB]
  catechol

  catechol

  Name origin: UniProt - CHECKED (C)

  CHEBI:18135

  Formula: C6H6O2
  Charge: 0

  ChEBI compound status: CHECKED (C)

  

  +

  O₂

  O2

  Name origin: UniProt - CHECKED (C)

  CHEBI:15379

  Formula: O2
  Charge: 0

  ChEBI compound status: CHECKED (C)

  

  <?>

  cis,cis-muconate

  cis,cis-muconate

  Name origin: UniProt - CHECKED (C)

  CHEBI:32379

  Formula: C6H4O4
  Charge: -2

  ChEBI compound status: CHECKED (C)

  

  +

  2

  H⁺

  H(+)

  Name origin: UniProt - CHECKED (C)

  CHEBI:15378

  Formula: H
  Charge: 1

  ChEBI compound status: CHECKED (C)

  

Cofactor

• Fe cation

Comments:

Requires Fe³⁺. Involved in the metabolism of nitro-aromatic compounds by a strain of Pseudomonas putida. Formerly EC 1.13.1.1 and 1.99.2.2.

Links to other databases

References

1. Hayaishi, O.
   Direct oxygenation by O₂, oxygenases.
   In: Boyer, P.D., Lardy, H. and Myrbäck, K. (Eds.) The Enzymes, 2nd ed. vol. 8, Academic Press, New York, 1963, 353-371
2. Hayaishi, O., Katagiri, M. and Rothberg, S.
   Studies on oxygenases: pyrocatechase.
   J. Biol. Chem. 229: 905-920 (1957).
3. Sistrom, W.R. and Stanier, R.Y.
   The mechanism of formation of β-ketoadipic acid by bacteria.
   J. Biol. Chem. 210: 821-836 (1954).
4. Zeyer, J., Kocher, H.P.
   and Timmis, N.Influence of para-substituents on the oxidative metabolism of o-nitrophenols by Pseudomonas putida B2.
   Appl. Environ. Microbiol. 52: 334-339 (1986). [PMID: 3752997]

[EC 1.13.11.1 created 1961 as EC 1.99.2.2, transferred 1965 to EC 1.13.1.1, transferred 1972 to EC 1.13.11.1]