EC 1.1.1.94 - Glycerol-3-phosphate dehydrogenase [NAD(P)+]

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IntEnz Enzyme Nomenclature
EC 1.1.1.94

Names

Accepted name:
glycerol-3-phosphate dehydrogenase [NAD(P)+]
Other names:
L-glycerol-3-phosphate:NAD(P) oxidoreductase
glycerol 3-phosphate dehydrogenase (NADP)
glycerol phosphate dehydrogenase (nicotinamide adenine dinucleotide (phosphate))
glycerol 3-phosphate dehydrogenase (NAD(P))
Systematic name:
sn-glycerol-3-phosphate:NAD(P)+ 2-oxidoreductase

Reactions

Comments:

The enzyme from Escherichia coli shows specificity for the B side of NADPH.

Links to other databases

Enzymes and pathways: NC-IUBMB , BRENDA , ExplorEnz , ENZYME@ExPASy , KEGG , MetaCyc , UniPathway
Protein domains and families: PROSITE:PDOC00740
Structural data: CSA , EC2PDB
Gene Ontology: GO:0047952
CAS Registry Number: 37250-30-9
UniProtKB/Swiss-Prot: (593) [show] [UniProt]

References

  1. Kito, M. and Pizer, L.I.
    Purification and regulatory properties of the biosynthetic L-glycerol 3-phosphate dehydrogenase from Escherichia coli.
    J. Biol. Chem. 244: 3316-3323 (1969). [PMID: 4389388]
  2. Edgar, J.R. and Bell, R.M.
    Biosynthesis in Escherichia coli fo sn-glycerol 3-phosphate, a precursor of phospholipid.
    J. Biol. Chem. 253: 6348-6353 (1978). [PMID: 355254]
  3. Edgar, J.R. and Bell, R.M.
    Biosynthesis in Escherichia coli of sn-glycerol 3-phosphate, a precursor of phospholipid. Kinetic characterization of wild type and feedback-resistant forms of the biosynthetic sn-glycerol-3-phosphate dehydrogenase.
    J. Biol. Chem. 253: 6354-6363 (1978). [PMID: 28326]
  4. Edgar, J.R. and Bell, R.M.
    Biosynthesis in Escherichia coli of sn-glycerol-3-phosphate, a precursor of phospholipid. Further kinetic characterization of wild type and feedback-resistant forms of the biosynthetic sn-glycerol-3-phosphate dehydrogenase.
    J. Biol. Chem. 255: 3492-3497 (1980). [PMID: 6767719]

[EC 1.1.1.94 created 1972, modified 2005]