EC 1.1.1.88 - Hydroxymethylglutaryl-CoA reductase

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IntEnz Enzyme Nomenclature
EC 1.1.1.88

Names

Accepted name:
hydroxymethylglutaryl-CoA reductase
Other names:
3-hydroxy-3-methylglutaryl coenzyme A reductase
β-hydroxy-β-methylglutaryl CoA-reductase
β-hydroxy-β-methylglutaryl coenzyme A reductase
hydroxymethylglutaryl coenzyme A reductase
Systematic name:
(R)-mevalonate:NAD+ oxidoreductase (CoA-acylating)

Reaction

Links to other databases

Enzymes and pathways: NC-IUBMB , BRENDA , DIAGRAM , ERGO , ExplorEnz , ENZYME@ExPASy , KEGG , MetaCyc , UniPathway
Protein domains and families: PROSITE:PDOC00064
Structural data: CSA , EC2PDB
Gene Ontology: GO:0042282
CAS Registry Number: 37250-24-1
UniProtKB/Swiss-Prot:

References

  1. Fimognari, G.M. and Rodwell, V.W.
    Substrate-competitive inhibition of bacterial mevalonate:nicotinamide-adenine dinucleotide oxidoreductase (acylating CoA).
    Biochemistry 4: 2086-2090 (1965).

[EC 1.1.1.88 created 1972, modified 2002]