EC 1.1.1.52 - 3α-hydroxycholanate dehydrogenase (NAD+)

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IntEnz Enzyme Nomenclature
EC 1.1.1.52

Names

Accepted name:
3α-hydroxycholanate dehydrogenase (NAD+)
Other names:
α-hydroxy-cholanate dehydrogenase
lithocholate:NAD+ oxidoreductase
3α-hydroxycholanate dehydrogenase
Systematic name:
lithocholate:NAD+ 3-oxidoreductase

Reaction

Comments:

Also acts on other 3α-hydroxysteroids with an acidic side-chain. cf. EC 1.1.1.392, 3α-hydroxycholanate dehydrogenase (NADP+).

Links to other databases

Enzymes and pathways: NC-IUBMB , BRENDA , DIAGRAM , ExplorEnz , ENZYME@ExPASy , KEGG , MetaCyc , UniPathway
Structural data: CSA , EC2PDB
Gene Ontology: GO:0047043
CAS Registry Number: 9028-57-3

References

  1. Hayaishi, O., Saito, Y., Jakoby, W.B. and Stohlman, E.F.
    Reversible enzymatic oxidation of bile acids.
    Arch. Biochem. 56: 554-555 (1955). [PMID: 14377608]

[EC 1.1.1.52 created 1961, modified 1976, modified 2016]