EC 1.1.1.282 - Quinate/shikimate dehydrogenase

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IntEnz Enzyme Nomenclature
EC 1.1.1.282

Names

Accepted name:
quinate/shikimate dehydrogenase
Other name:
YdiB
Systematic name:
L-quinate:NAD(P)+ 3-oxidoreductase

Reactions

Comments:

This is the second shikimate dehydrogenase enzyme found in Escherichia coli and differs from EC 1.1.1.25, shikimate 3-dehydrogenase, in that it can use both quinate and shikimate as substrate and either NAD+ or NADP+ as acceptor.

Links to other databases

Enzymes and pathways: NC-IUBMB , BRENDA , DIAGRAM , ExplorEnz , ENZYME@ExPASy , KEGG , MetaCyc , UniPathway
Structural data: CSA , EC2PDB
Gene Ontology: GO:0030266 , GO:0052733 , GO:0052734 , GO:0004764
UniProtKB/Swiss-Prot: (37) [show] [UniProt]

References

  1. Michel, G., Roszak, A.W., Sauvé, V., Maclean, J., Matte, A., Coggins, J.R., Cygler, M. and Lapthorn, A.J.
    Structures of shikimate dehydrogenase AroE and its paralog YdiB. A common structural framework for different activities.
    J. Biol. Chem. 278: 19463-19472 (2003). [PMID: 12637497]
  2. Benach, J., Lee, I., Edstrom, W., Kuzin, A.P., Chiang, Y., Acton, T.B., Montelione, G.T., Hunt and J.F.
    The 2.3-Å crystal structure of the shikimate 5-dehydrogenase orthologue YdiB from Escherichia coli suggests a novel catalytic environment for an NAD-dependent dehydrogenase.
    J. Biol. Chem. 278: 19176-19182 (2003). [PMID: 12624088]

[EC 1.1.1.282 created 2004]