EC 1.1.1.231 - 15-hydroxyprostaglandin-I dehydrogenase (NADP+)

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IntEnz Enzyme Nomenclature
EC 1.1.1.231

Names

Accepted name:
15-hydroxyprostaglandin-I dehydrogenase (NADP+)
Other names:
NADP-linked 15-hydroxyprostaglandin (prostacyclin) dehydrogenase
NADP+-dependent PGI2-specific 15-hydroxyprostaglandin dehydrogenase
PG I2 dehydrogenase
prostacyclin dehydrogenase
Systematic name:
(5Z,13E)-(15S)-6,9α-epoxy-11α,15-dihydroxyprosta-5,13-dienoate:NADP+ 15-oxidoreductase

Reaction

Comments:

Specific for prostaglandin I2.

Links to other databases

Enzymes and pathways: NC-IUBMB , BRENDA , ExplorEnz , ENZYME@ExPASy , KEGG , MetaCyc , UniPathway
Structural data: CSA , EC2PDB
Gene Ontology: GO:0047033
CAS Registry Number: 79468-49-8

References

  1. Korff, J.M. and Jarabak, J.
    Isolation and properties of an NADP+-dependent PGI2-specific 15-hydroxyprostaglandin dehydrogenase from rabbit kidney.
    Methods Enzymol. 86: 152-155 (1982). [PMID: 6182444]

[EC 1.1.1.231 created 1990]