EC 1.1.1.178 - 3-hydroxy-2-methylbutyryl-CoA dehydrogenase

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IntEnz Enzyme Nomenclature
EC 1.1.1.178

Names

Accepted name:
3-hydroxy-2-methylbutyryl-CoA dehydrogenase
Other names:
2-methyl-3-hydroxy-butyryl CoA dehydrogenase
2-methyl-3-hydroxybutyryl coenzyme A dehydrogenase
Systematic name:
(2S,3S)-3-hydroxy-2-methylbutanoyl-CoA:NAD+ oxidoreductase

Reaction

Comments:

Also acts, more slowly, on (2S,3S)-2-hydroxy-3-methylpentanoyl-CoA.

Links to other databases

Enzymes and pathways: NC-IUBMB , BRENDA , ExplorEnz , ENZYME@ExPASy , KEGG , MetaCyc , UniPathway
Protein domains and families: PROSITE:PDOC00060
Structural data: CSA , EC2PDB
Gene Ontology: GO:0047015
CAS Registry Number: 52227-66-4
UniProtKB/Swiss-Prot:

References

  1. Conrad, R.S., Massey, L.K. and Sokatch, J.R.
    D- and L-isoleucine metabolism and regulation of their pathways in Pseudomonas putida.
    J. Bacteriol. 118: 103-111 (1974). [PMID: 4150713]

[EC 1.1.1.178 created 1981]