EC 1.1.1.149 - 20α-hydroxysteroid dehydrogenase

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IntEnz Enzyme Nomenclature
EC 1.1.1.149

Names

Accepted name:
20α-hydroxysteroid dehydrogenase
Other names:
20α-HSD
20α-HSDH
20α-hydroxy steroid dehydrogenase
Systematic name:
20α-hydroxysteroid:NAD(P)+ 20-oxidoreductase

Reactions

Comments:

Re-specific with respect to NAD(P)+ (cf. EC 1.1.1.62 estradiol 17β-dehydrogenase).

Links to other databases

Enzymes and pathways: NC-IUBMB , BRENDA , ExplorEnz , ENZYME@ExPASy , KEGG , MetaCyc , UniPathway
Protein domains and families: PROSITE:PDOC00061
Structural data: CSA , EC2PDB
Gene Ontology: GO:0047006
CAS Registry Number: 9040-08-8
UniProtKB/Swiss-Prot:

References

  1. Shikita, M., Inano, H. and Tamaoki, B.
    Further studies on 20α-hydroxysteroid dehydrogenase of rat testes.
    Biochemistry 6: 1760-1764 (1967). [PMID: 4382486]
  2. Strickler, R.C., Tobias, B. and Covey, D.F.
    Human placental 17β-estradiol dehydrogenase and 20α-hydroxysteroid dehydrogenase. Two activities at a single enzyme active site.
    J. Biol. Chem. 256: 316-321 (1981). [PMID: 6935192]

[EC 1.1.1.149 created 1972, deleted 1983, reinstated 1986]