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What is this view?

Binary interactions

In this tab, we display the list of interactions that you have selected using one of our search features. Despite the fact that our data are annotated to accurately reflect the interactions reported in scientific literature, the data is shown in this view as binary interactions. Whenever the data was reported as a co-complex involving more than two molecules, we store it as such in the IntAct database and post-process it so the portal can show it as binary interaction. This post-processing is the Spoke Expansion model (connects bait to all preys):



sourceExp

At any moment you can choose to display the expansion column in this view in order to see which interaction are spoke expanded and which are not.

Description of what has changed

  • We have added more download options to allow users to retrieve their interaction set using more standard formats such as PSI-MI XML and PSIMITAB (version 2.5, 2.6 or 2.7) but also XGMML, RDF and Biopax (level 2 and 3).
  • We have now four different table views : minimal(molecule names and interaction AC), basic (minimal + molecule links, interaction detection method, negative), standard(minimal + molecule species, confidences, publication details, experiment details), expanded (standard + more experiment details) and complete (all mitab 2.7 columns).

Configuring the view to your need"

In the header of the interaction table you will find a button: ‘Change Column Display’ that will show you all the columns/Table views available and allow you to update the current selected set.

Downloading the data into Standard formats"

In the header of the interaction table you will find a drop down list that contains all the formats currently supported when downloading the interaction data. Select one of them and click the export button next to the list. Please note that PSI-MI XML is only available when the interaction set is no bigger than 1000 interactions.

Opening the interaction details"

Clicking on the magnifying glass in the first column of the interaction table will open the details of the corresponding interaction in the Interaction Details tab, giving you access to more details of the manually curated record.

What is this view?

Browsing (Browse Tab)

This tab is meant to give you access to more content based on the currently selected set of interactions. Please note that linking to third party resources will only include up to 200 molecules , if you exceed this number you will see the warning icon (This number has been reduced to 125 molecules for mRNA expression). Now let’s look at the features available to you:

Limiting the scope of the current dataset with the Uniprot Taxonomy ontology

Allows users to browse the Uniprot Taxonomy hierarchy as a tree and select terms in order to narrow down their dataset. Once a term is selected, you are taken back to the interaction tab to review your dataset.

Limiting the scope of the current dataset with the GO ontology

Allows users to browse the GO hierarchy as a tree and select terms in order to narrow down their dataset. Once a term is selected, you are taken back to the interaction tab to review your dataset.

Limiting the scope of the current dataset with the ChEBI ontology

Allows users to browse the ChEBI hierarchy as a tree and select terms in order to narrow down their dataset. Once a term is selected, you are taken back to the interaction tab to review your dataset.

Bulk linking to third party resources by using involved proteins

  • Proteins by Reactome pathway: Sends your proteins to the Reactome SkyPainter that will show you the pathways in which these molecules are know to play a role.
  • Proteins by Chromosomal location: Sends your list of proteins to Ensembl’s Karyotype viewer and overlays the proteins on the chromosomes.
  • Proteins by mRNA expression: Sends your set of proteins to the ArrayExpress Atlas that will show the known gene expression based on experimental studies.
What is this view?

Searching Interactions (Search Tab)

As you can see in this tab we are now trying to give you more targeted choice to do your queries, please note that the examples provided in this tab are live links so you can simply click them to see the resulting interactions sets.

Using the Quick Search

In this search panel you are free to type anything that might relate to interactions, whether it is properties of their interactor (gene name, identifiers, GO term…) or more specific to the interaction like publication, authors, experimental detection method, ...

Some examples:

  • Try the query: imatinib
    This is a drug for which we have curated a number of interactions.
    Once you press the search button you should be taken to the Interaction Tab that lists 130 binary interactions.
    If you want to construct more complex queries we recommend you take a look at the Molecular Interaction Query Language, accessible from the quick search panel.
  • Try the query: species:yeast AND type:"direct interaction"
    This query selects all interactions involving yeast interactors that have been shown to have direct interactions. If you customize the column display of the interaction tab, you will see that not only “direct interaction” have been selected but also children terms in the PSI-MI ontology.

Using the Ontology Search

Open the Rearch Tab. This panel is specialised to give you an easy access to ontology search. So far you can search on 4 ontologies:

  • Gene Ontology
  • InterPro
  • PSI-MI
  • ChEBI

Whenever you start typing a query in this search panel, the system will search as you type and propose a list of matching controlled vocabulary terms. You can then select one of them and select matching interactions.

For example, type: cancer
You will be presented with a few choices, please note that each term is followed by the count of matching interactions in the IntAct database.

Select a term with the mouse or using the keyboard cursor keys and you will be taken to the interaction tab.

Searching the Compound chemical structure

In this panel you will be able to draw all or part of a chemical structure and search for chemical compounds. If you get any matched, you can then see all interactions involving them.

First you have to open up the chemical search panel so that the applet can load, it might take a few seconds. Then you can start drawing your structure, for instance:

Once you have drawn your structure, select Similarity and press Search. You should be presented with a list of matching compound. Now choose one molecule and click the link: IntAct interactions. You will be taken to the interaction tab to review the data.

Complex Expansion

Binary interactions generated by co-complex expansion

Why should you care about complex expansion ?

Some experimental methods such as Tandem Affinity Purification do generate molecular interactions that can involve more than 2 molecules. Despite the fact that IntAct curation team do capture the molecular interaction as they were reported in the corresponding experiment, when you search using the intact web site, the results of your query is always shown as set of binary interactions (i.e. 2 molecules). We would like to draw your attention on the fact that whenever the reported interaction was a co-complex we do apply an expansion algorithm that transform this n-ary interaction into a set of binary interactions. While none of these agorithms is perfect and will very likely generate some false positive interactions, it is useful to present the data in a consistent manner. Bear in mind that we will strive to differentiate in the search results which interactions are a real experimental binary from expanded ones.

Existing expansion algorithm

There are several known algorithm allowing to transform an n-ary interaction into a set of binaries. The illustration below present the two well known expansion model and illustrates why they can be incorrect.



sourceExp

  • Spoke expansion: Links the bait molecule to all prey molecules. If N is the count of molecule in the complex, it generated N-1 binary interactions.
  • Matrix expansion: Links all molecule to all other molecule present in the complex. If N is the count of molecule in the complex, it generated (N*(N-1))/2 binary interactions.

Now the issue (as illustrated at the bottom right of the diagram above) with these two models lies in the fact that the real complex might not be articulated around the experimental bait but instead, this bait might be linked to a smaller complex, hence most binary interaction generated by spoke and matrix expansion result in false positive.



PSICQUIC

How is the number of interactions in other databases obtained?

PSICQUIC is a standard way to access molecular interaction databases across which it repeats the same query. The number of databases providing data may vary, depending on the status of their services and only those that are active are used in this query. By clicking on the number of interactions you will be redirected to the PSICQUIC View, where you can browse the results in those other resources.

The services currently active are:

Check the PSICQUIC site for more information.

IMEx

What is the significance of the IMEx dataset?"

IMEx is a network of databases which have agreed to supply a non-redundant set of data expertly manually annotated to the same consistent detailed standard which, as such, represents a high-quality subset of the data each individually provides. The number of databases providing data may vary, depending on the status of their services and only those that are active are used in this query. By clicking on the number of interactions you will be redirected to the IMEx View, where you can browse the results in those other resources.

The services currently active are:

Check the IMEx site for more information.

What is this view?

Representation of Experimental Features

This section shows the graphical representation of experimental features, where each participant is represented as a white rectangle with a black border and a line for each hundredth amino acid. All available features are attached to their associated participant and their categories are represented in the right side of the legend. The left side of the legend dynamically shows the range statuses occuring in the shown interaction. These are the possible range statuses:

sourceExp

Interacting with the widget

Hover over a feature to see more information in a tooltip.
sourceExp

To display a single interacting region click on it and click again to display all interacting regions.
Displaying all interacting regionsDisplaying one interacting region
sourceExpsourceExp
What is this view?

Dynamic molecular interaction data

This section shows the graphical representation of dynamic molecular interactions. By default it displays all the interactions from one experiment using radio buttons to allow users to highlight interactions in different variable conditions.

Publication

PubMed Id: 23075850

Journal: Nature (0028-0836)

Year of Publication: 2012

Title: Progressive degeneration of human neural stem cells caused by pathogenic LRRK2.

Author List: Liu G.H., Qu J., Suzuki K., Nivet E., Li M., Montserrat N., Yi F., Xu X., Ruiz S., Zhang W., Wagner U., Kim A., Ren B., Li Y., Goebl A., Kim J., Soligalla R.D., Dubova I., Thompson J., Yates J., Esteban C.R., Sancho-Martinez I., Izpisua Belmonte J.C.

Cross References:

Database
Identifier
Secondary identifier
Qualifier
-
-

Annotations:

Topic
Text
Parkinsons - Interactions investigated in the context of Parkinsons disease
Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.

Experiment (1 interaction)

Accession: EBI-6515032

Name: liu-2012d-1

Host organism: Homo sapiens 293 cells transformed with SV40 large T antigen

Organism: Homo sapiens 293 cells transformed with SV40 large T antigen

Accession: EBI-308002

Name: human-293t

Description: Homo sapiens 293 cells transformed with SV40 large T antigen

Cross References:

Database
Identifier
Secondary identifier
Qualifier
human
-

Interaction Detection Method: anti tag coip

Interaction detection method: anti tag coip
Accession: EBI-90

Name: anti tag coip

Description: anti tag coimmunoprecipitation

Cross References:
Database
Identifier
Secondary identifier
Qualifier
psi-mi
MI:0007
-
identity
pubmed
7708014
-
primary-reference


Annotations:
Topic
Text
definition
A specific antibody for the molecule of interest is not available, therefore the bait protein is expressed as a hybrid protein fused to a tag peptide/protein for which efficient and specific antibodies or a specific ligand are available.


Participant Identification Method: mudpit

Participant identification method: mudpit
Accession: EBI-933988

Name: mudpit

Description: multidimensional protein identification technology

Cross References:
Database
Identifier
Secondary identifier
Qualifier
psi-mi
MI:0658
-
identity
pubmed
11231557
-
primary-reference


Annotations:
Topic
Text
definition
MudPIT is a method for rapid and large-scale protein identification by multidimensional liquid chromatography associated with tandem mass spectrometry. The chromatography step consists of strong cation exchange material back-to-back with reversed phase material inside fused silica capillaries. The peptides bound to the cation-exchange resin are freed by the gradually increasing salt concentration of the buffer and are subsequently retained by the reversed phase resin. Increasing buffers hydrophobicity progressively elute peptides from the reversed phase packing directly into the mass spectrometer. Typically this mass spectrometer will be a tandem electrospray, so peptides undergo ionization in the liquid phase, are separated in a primary mass spectrometer, analysed in the second mass spectrometer and identified.


Cross References:

Database
Identifier
Secondary identifier
Qualifier
-
-

Annotations:

Topic
Text
belmonte@salk.edu, ghliu@ibp.ac.cn
imex curation
Tubulin beta-2C and EF-1-alpha-1 (eukaryotic translation elongation factor 1 alpha) have not been entered as they cannot be identified from the peptide sequences given. p65 (from figure S2A) has not been entered, as it cannot be identified, and there appears to be no peptide sequences given for this protein. .
Only protein-protein interactions
-

Interaction

Accession: EBI-6515052

Name: lrrk2-acin1-7

Description: -

Type: association

Interaction type: association
Accession: EBI-1813191

Name: association

Description: association

Cross References:
Database
Identifier
Secondary identifier
Qualifier
pubmed
14755292
-
primary-reference
psi-mi
MI:0914
-
identity


Annotations:
Topic
Text
definition
Interaction between molecules that may participate in formation of one, but possibly more, physical complexes. Often describes a set of molecules that are co-purified in a single pull-down or coimmunoprecipitation but might participate in formation of distinct physical complexes sharing a common bait.


Cross References:

Database
Identifier
Secondary identifier
Qualifier
-

Annotations:

Topic
Text
Table S1, S2A.

Participants (38)

Legend:
A
Annotation and Cross Reference  
P
Experimental Parameter   
S
Stoichiometry   
F
Experimental Feature
C
Participant Confidence
pp12pp
#
Name
Links
Primary Identifier
Aliases
Description
Species
Expression system
Experimental role
Biological role
Interactor type
More...
pp12pp
1
EBI-5323863
 logo
LRRK2
PARK8
Dardarin
Leucine-rich repeat serine/threonine-protein kinase 2
Homo sapiens
Organism Details

Accession: EBI-874

Name: human

Description: Homo sapiens

Cross References:

Database
Identifier
Secondary identifier
Qualifier
human

Expressed In Details

Accession:

Name:

-
bait
Experimental role: bait
Accession: EBI-49

Name: bait

Description: bait

Cross References:
Database
Identifier
Secondary identifier
Qualifier
psi-mi
MI:0496
-
identity
pubmed
14755292
-
primary-reference


Annotations:
Topic
Text
definition
Molecule experimentally treated to capture its interacting partners.


unspecified role
Biological role: unspecified role
Accession: EBI-77781

Name: unspecified role

Description: unspecified role

Cross References:
Database
Identifier
Secondary identifier
Qualifier
psi-mi
MI:0499
-
identity
pubmed
14755292
-
primary-reference


Annotations:
Topic
Text
definition
Role not specified or not applicable to the data.


protein
Interactor type: protein
Accession: EBI-619654

Name: protein

Description: protein

Cross References:
Database
Identifier
Secondary identifier
Qualifier
psi-mi
MI:0326
-
identity
pubmed
14755292
-
primary-reference
so
SO:0000358
-
see-also


Annotations:
Topic
Text
definition
A linear polymer of amino acids joined by peptide bonds in a specific sequence.


A
Participant: Leucine-rich repeat serine/threonine-protein kinase 2

Participant: Leucine-rich repeat serine/threonine-protein kinase 2

Accession: EBI-6515054

Name: EBI-5323863

P
Participant: Leucine-rich repeat serine/threonine-protein kinase 2

Participant: Leucine-rich repeat serine/threonine-protein kinase 2

Accession: EBI-6515054

Name: EBI-5323863

Parameters:

Type
Value
Unit
Base
Exponent
Uncertainty
No records found.


S
Participant: Leucine-rich repeat serine/threonine-protein kinase 2

Participant: Leucine-rich repeat serine/threonine-protein kinase 2

Accession: EBI-6515054

Name: EBI-5323863

Stoichiometry: 0.0

F
Participant: Leucine-rich repeat serine/threonine-protein kinase 2

Participant: Leucine-rich repeat serine/threonine-protein kinase 2

Accession: EBI-6515054

Name: EBI-5323863

Features:

Legend:
A
Annotation and Cross Reference  
Feature Name
Feature Type
Detection Method
Range positions
More...
region
  • ?-?
  • A
    Feature: EBI-6515469

    Feature: region

    Accession: EBI-6515469

    Name: region

    gly2019ser
  • 2019-2019
  • A
    Feature: EBI-6515058

    Feature: gly2019ser

    Accession: EBI-6515058

    Name: gly2019ser


    C
    Participant: Leucine-rich repeat serine/threonine-protein kinase 2

    Participant: Leucine-rich repeat serine/threonine-protein kinase 2

    Accession: EBI-6515054

    Name: EBI-5323863

    Confidences:

    Type
    Value
    No records found.

    2
    EBI-352602
     logo
    KIAA0723
    MATR3
    Matrin-3
    Homo sapiens
    Organism Details

    Accession: EBI-874

    Name: human

    Description: Homo sapiens

    Cross References:

    Database
    Identifier
    Secondary identifier
    Qualifier
    human

    Expressed In Details

    Accession:

    Name:

    -
    prey
    Experimental role: prey
    Accession: EBI-58

    Name: prey

    Description: prey

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    psi-mi
    MI:0498
    -
    identity
    pubmed
    14755292
    -
    primary-reference


    Annotations:
    Topic
    Text
    definition
    Molecule experimentally identified as being captured by a given bait.


    unspecified role
    Biological role: unspecified role
    Accession: EBI-77781

    Name: unspecified role

    Description: unspecified role

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    psi-mi
    MI:0499
    -
    identity
    pubmed
    14755292
    -
    primary-reference


    Annotations:
    Topic
    Text
    definition
    Role not specified or not applicable to the data.


    protein
    Interactor type: protein
    Accession: EBI-619654

    Name: protein

    Description: protein

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    psi-mi
    MI:0326
    -
    identity
    pubmed
    14755292
    -
    primary-reference
    so
    SO:0000358
    -
    see-also


    Annotations:
    Topic
    Text
    definition
    A linear polymer of amino acids joined by peptide bonds in a specific sequence.


    A
    Participant: Matrin-3

    Participant: Matrin-3

    Accession: EBI-6515387

    Name: EBI-352602

    P
    Participant: Matrin-3

    Participant: Matrin-3

    Accession: EBI-6515387

    Name: EBI-352602

    Parameters:

    Type
    Value
    Unit
    Base
    Exponent
    Uncertainty
    No records found.


    S
    Participant: Matrin-3

    Participant: Matrin-3

    Accession: EBI-6515387

    Name: EBI-352602

    Stoichiometry: 0.0

    F
    Participant: Matrin-3

    Participant: Matrin-3

    Accession: EBI-6515387

    Name: EBI-352602

    Features:

    Legend:
    A
    Annotation and Cross Reference  
    Feature Name
    Feature Type
    Detection Method
    Range positions
    More...
    No records found.

    C
    Participant: Matrin-3

    Participant: Matrin-3

    Accession: EBI-6515387

    Name: EBI-352602

    Confidences:

    Type
    Value
    No records found.

    3
    EBI-395393
     logo
    TMPO
    LAP2
    Thymopoietin isoform alpha

    [+1]
    Lamina-associated polypeptide 2, isoform alpha
    Homo sapiens
    Organism Details

    Accession: EBI-874

    Name: human

    Description: Homo sapiens

    Cross References:

    Database
    Identifier
    Secondary identifier
    Qualifier
    human

    Expressed In Details

    Accession:

    Name:

    -
    prey
    Experimental role: prey
    Accession: EBI-58

    Name: prey

    Description: prey

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    psi-mi
    MI:0498
    -
    identity
    pubmed
    14755292
    -
    primary-reference


    Annotations:
    Topic
    Text
    definition
    Molecule experimentally identified as being captured by a given bait.


    unspecified role
    Biological role: unspecified role
    Accession: EBI-77781

    Name: unspecified role

    Description: unspecified role

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    psi-mi
    MI:0499
    -
    identity
    pubmed
    14755292
    -
    primary-reference


    Annotations:
    Topic
    Text
    definition
    Role not specified or not applicable to the data.


    protein
    Interactor type: protein
    Accession: EBI-619654

    Name: protein

    Description: protein

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    psi-mi
    MI:0326
    -
    identity
    pubmed
    14755292
    -
    primary-reference
    so
    SO:0000358
    -
    see-also


    Annotations:
    Topic
    Text
    definition
    A linear polymer of amino acids joined by peptide bonds in a specific sequence.


    A
    Participant: Lamina-associated polypeptide 2, isoform alpha

    Participant: Lamina-associated polypeptide 2, isoform alpha

    Accession: EBI-6515388

    Name: EBI-395393

    P
    Participant: Lamina-associated polypeptide 2, isoform alpha

    Participant: Lamina-associated polypeptide 2, isoform alpha

    Accession: EBI-6515388

    Name: EBI-395393

    Parameters:

    Type
    Value
    Unit
    Base
    Exponent
    Uncertainty
    No records found.


    S
    Participant: Lamina-associated polypeptide 2, isoform alpha

    Participant: Lamina-associated polypeptide 2, isoform alpha

    Accession: EBI-6515388

    Name: EBI-395393

    Stoichiometry: 0.0

    F
    Participant: Lamina-associated polypeptide 2, isoform alpha

    Participant: Lamina-associated polypeptide 2, isoform alpha

    Accession: EBI-6515388

    Name: EBI-395393

    Features:

    Legend:
    A
    Annotation and Cross Reference  
    Feature Name
    Feature Type
    Detection Method
    Range positions
    More...
    No records found.

    C
    Participant: Lamina-associated polypeptide 2, isoform alpha

    Participant: Lamina-associated polypeptide 2, isoform alpha

    Accession: EBI-6515388

    Name: EBI-395393

    Confidences:

    Type
    Value
    No records found.

    4
    EBI-968218
     logo
    LMNB1
    LMN2
    LMNB
    Lamin-B1
    Homo sapiens
    Organism Details

    Accession: EBI-874

    Name: human

    Description: Homo sapiens

    Cross References:

    Database
    Identifier
    Secondary identifier
    Qualifier
    human

    Expressed In Details

    Accession:

    Name:

    -
    prey
    Experimental role: prey
    Accession: EBI-58

    Name: prey

    Description: prey

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    psi-mi
    MI:0498
    -
    identity
    pubmed
    14755292
    -
    primary-reference


    Annotations:
    Topic
    Text
    definition
    Molecule experimentally identified as being captured by a given bait.


    unspecified role
    Biological role: unspecified role
    Accession: EBI-77781

    Name: unspecified role

    Description: unspecified role

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    psi-mi
    MI:0499
    -
    identity
    pubmed
    14755292
    -
    primary-reference


    Annotations:
    Topic
    Text
    definition
    Role not specified or not applicable to the data.


    protein
    Interactor type: protein
    Accession: EBI-619654

    Name: protein

    Description: protein

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    psi-mi
    MI:0326
    -
    identity
    pubmed
    14755292
    -
    primary-reference
    so
    SO:0000358
    -
    see-also


    Annotations:
    Topic
    Text
    definition
    A linear polymer of amino acids joined by peptide bonds in a specific sequence.


    A
    Participant: Lamin-B1

    Participant: Lamin-B1

    Accession: EBI-6515389

    Name: EBI-968218

    P
    Participant: Lamin-B1

    Participant: Lamin-B1

    Accession: EBI-6515389

    Name: EBI-968218

    Parameters:

    Type
    Value
    Unit
    Base
    Exponent
    Uncertainty
    No records found.


    S
    Participant: Lamin-B1

    Participant: Lamin-B1

    Accession: EBI-6515389

    Name: EBI-968218

    Stoichiometry: 0.0

    F
    Participant: Lamin-B1

    Participant: Lamin-B1

    Accession: EBI-6515389

    Name: EBI-968218

    Features:

    Legend:
    A
    Annotation and Cross Reference  
    Feature Name
    Feature Type
    Detection Method
    Range positions
    More...
    No records found.

    C
    Participant: Lamin-B1

    Participant: Lamin-B1

    Accession: EBI-6515389

    Name: EBI-968218

    Confidences:

    Type
    Value
    No records found.

    5
    EBI-351935
     logo
    LMNA
    LMN1
    Prelamin-A/C
    Homo sapiens
    Organism Details

    Accession: EBI-874

    Name: human

    Description: Homo sapiens

    Cross References:

    Database
    Identifier
    Secondary identifier
    Qualifier
    human

    Expressed In Details

    Accession:

    Name:

    -
    prey
    Experimental role: prey
    Accession: EBI-58

    Name: prey

    Description: prey

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    psi-mi
    MI:0498
    -
    identity
    pubmed
    14755292
    -
    primary-reference


    Annotations:
    Topic
    Text
    definition
    Molecule experimentally identified as being captured by a given bait.


    unspecified role
    Biological role: unspecified role
    Accession: EBI-77781

    Name: unspecified role

    Description: unspecified role

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    psi-mi
    MI:0499
    -
    identity
    pubmed
    14755292
    -
    primary-reference


    Annotations:
    Topic
    Text
    definition
    Role not specified or not applicable to the data.


    protein
    Interactor type: protein
    Accession: EBI-619654

    Name: protein

    Description: protein

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    psi-mi
    MI:0326
    -
    identity
    pubmed
    14755292
    -
    primary-reference
    so
    SO:0000358
    -
    see-also


    Annotations:
    Topic
    Text
    definition
    A linear polymer of amino acids joined by peptide bonds in a specific sequence.


    A
    Participant: Prelamin-A/C

    Participant: Prelamin-A/C

    Accession: EBI-6515390

    Name: EBI-351935

    P
    Participant: Prelamin-A/C

    Participant: Prelamin-A/C

    Accession: EBI-6515390

    Name: EBI-351935

    Parameters:

    Type
    Value
    Unit
    Base
    Exponent
    Uncertainty
    No records found.


    S
    Participant: Prelamin-A/C

    Participant: Prelamin-A/C

    Accession: EBI-6515390

    Name: EBI-351935

    Stoichiometry: 0.0

    F
    Participant: Prelamin-A/C

    Participant: Prelamin-A/C

    Accession: EBI-6515390

    Name: EBI-351935

    Features:

    Legend:
    A
    Annotation and Cross Reference  
    Feature Name
    Feature Type
    Detection Method
    Range positions
    More...
    No records found.

    C
    Participant: Prelamin-A/C

    Participant: Prelamin-A/C

    Accession: EBI-6515390

    Name: EBI-351935

    Confidences:

    Type
    Value
    No records found.

    6
    EBI-352869
     logo
    SAFB2
    KIAA0138
    Scaffold attachment factor B2
    Homo sapiens
    Organism Details

    Accession: EBI-874

    Name: human

    Description: Homo sapiens

    Cross References:

    Database
    Identifier
    Secondary identifier
    Qualifier
    human

    Expressed In Details

    Accession:

    Name:

    -
    prey
    Experimental role: prey
    Accession: EBI-58

    Name: prey

    Description: prey

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    psi-mi
    MI:0498
    -
    identity
    pubmed
    14755292
    -
    primary-reference


    Annotations:
    Topic
    Text
    definition
    Molecule experimentally identified as being captured by a given bait.


    unspecified role
    Biological role: unspecified role
    Accession: EBI-77781

    Name: unspecified role

    Description: unspecified role

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    psi-mi
    MI:0499
    -
    identity
    pubmed
    14755292
    -
    primary-reference


    Annotations:
    Topic
    Text
    definition
    Role not specified or not applicable to the data.


    protein
    Interactor type: protein
    Accession: EBI-619654

    Name: protein

    Description: protein

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    psi-mi
    MI:0326
    -
    identity
    pubmed
    14755292
    -
    primary-reference
    so
    SO:0000358
    -
    see-also


    Annotations:
    Topic
    Text
    definition
    A linear polymer of amino acids joined by peptide bonds in a specific sequence.


    A
    Participant: Scaffold attachment factor B2

    Participant: Scaffold attachment factor B2

    Accession: EBI-6515391

    Name: EBI-352869

    P
    Participant: Scaffold attachment factor B2

    Participant: Scaffold attachment factor B2

    Accession: EBI-6515391

    Name: EBI-352869

    Parameters:

    Type
    Value
    Unit
    Base
    Exponent
    Uncertainty
    No records found.


    S
    Participant: Scaffold attachment factor B2

    Participant: Scaffold attachment factor B2

    Accession: EBI-6515391

    Name: EBI-352869

    Stoichiometry: 0.0

    F
    Participant: Scaffold attachment factor B2

    Participant: Scaffold attachment factor B2

    Accession: EBI-6515391

    Name: EBI-352869

    Features:

    Legend:
    A
    Annotation and Cross Reference  
    Feature Name
    Feature Type
    Detection Method
    Range positions
    More...
    No records found.

    C
    Participant: Scaffold attachment factor B2

    Participant: Scaffold attachment factor B2

    Accession: EBI-6515391

    Name: EBI-352869

    Confidences:

    Type
    Value
    No records found.

    7
    EBI-348298
     logo
    SAFB
    HAP
    HET

    [+2]
    Scaffold attachment factor B1
    Homo sapiens
    Organism Details

    Accession: EBI-874

    Name: human

    Description: Homo sapiens

    Cross References:

    Database
    Identifier
    Secondary identifier
    Qualifier
    human

    Expressed In Details

    Accession:

    Name:

    -
    prey
    Experimental role: prey
    Accession: EBI-58

    Name: prey

    Description: prey

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    psi-mi
    MI:0498
    -
    identity
    pubmed
    14755292
    -
    primary-reference


    Annotations:
    Topic
    Text
    definition
    Molecule experimentally identified as being captured by a given bait.


    unspecified role
    Biological role: unspecified role
    Accession: EBI-77781

    Name: unspecified role

    Description: unspecified role

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    psi-mi
    MI:0499
    -
    identity
    pubmed
    14755292
    -
    primary-reference


    Annotations:
    Topic
    Text
    definition
    Role not specified or not applicable to the data.


    protein
    Interactor type: protein
    Accession: EBI-619654

    Name: protein

    Description: protein

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    psi-mi
    MI:0326
    -
    identity
    pubmed
    14755292
    -
    primary-reference
    so
    SO:0000358
    -
    see-also


    Annotations:
    Topic
    Text
    definition
    A linear polymer of amino acids joined by peptide bonds in a specific sequence.


    A
    Participant: Scaffold attachment factor B1

    Participant: Scaffold attachment factor B1

    Accession: EBI-6515392

    Name: EBI-348298

    P
    Participant: Scaffold attachment factor B1

    Participant: Scaffold attachment factor B1

    Accession: EBI-6515392

    Name: EBI-348298

    Parameters:

    Type
    Value
    Unit
    Base
    Exponent
    Uncertainty
    No records found.


    S
    Participant: Scaffold attachment factor B1

    Participant: Scaffold attachment factor B1

    Accession: EBI-6515392

    Name: EBI-348298

    Stoichiometry: 0.0

    F
    Participant: Scaffold attachment factor B1

    Participant: Scaffold attachment factor B1

    Accession: EBI-6515392

    Name: EBI-348298

    Features:

    Legend:
    A
    Annotation and Cross Reference  
    Feature Name
    Feature Type
    Detection Method
    Range positions
    More...
    No records found.

    C
    Participant: Scaffold attachment factor B1

    Participant: Scaffold attachment factor B1

    Accession: EBI-6515392

    Name: EBI-348298

    Confidences:

    Type
    Value
    No records found.

    8
    EBI-521611
     logo
    SP-H antigen
    NUMA1
    NUMA

    [+2]
    Nuclear mitotic apparatus protein 1
    Homo sapiens
    Organism Details

    Accession: EBI-874

    Name: human

    Description: Homo sapiens

    Cross References:

    Database
    Identifier
    Secondary identifier
    Qualifier
    human

    Expressed In Details

    Accession:

    Name:

    -
    prey
    Experimental role: prey
    Accession: EBI-58

    Name: prey

    Description: prey

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    psi-mi
    MI:0498
    -
    identity
    pubmed
    14755292
    -
    primary-reference


    Annotations:
    Topic
    Text
    definition
    Molecule experimentally identified as being captured by a given bait.


    unspecified role
    Biological role: unspecified role
    Accession: EBI-77781

    Name: unspecified role

    Description: unspecified role

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    psi-mi
    MI:0499
    -
    identity
    pubmed
    14755292
    -
    primary-reference


    Annotations:
    Topic
    Text
    definition
    Role not specified or not applicable to the data.


    protein
    Interactor type: protein
    Accession: EBI-619654

    Name: protein

    Description: protein

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    psi-mi
    MI:0326
    -
    identity
    pubmed
    14755292
    -
    primary-reference
    so
    SO:0000358
    -
    see-also


    Annotations:
    Topic
    Text
    definition
    A linear polymer of amino acids joined by peptide bonds in a specific sequence.


    A
    Participant: Nuclear mitotic apparatus protein 1

    Participant: Nuclear mitotic apparatus protein 1

    Accession: EBI-6515393

    Name: EBI-521611

    P
    Participant: Nuclear mitotic apparatus protein 1

    Participant: Nuclear mitotic apparatus protein 1

    Accession: EBI-6515393

    Name: EBI-521611

    Parameters:

    Type
    Value
    Unit
    Base
    Exponent
    Uncertainty
    No records found.


    S
    Participant: Nuclear mitotic apparatus protein 1

    Participant: Nuclear mitotic apparatus protein 1

    Accession: EBI-6515393

    Name: EBI-521611

    Stoichiometry: 0.0

    F
    Participant: Nuclear mitotic apparatus protein 1

    Participant: Nuclear mitotic apparatus protein 1

    Accession: EBI-6515393

    Name: EBI-521611

    Features:

    Legend:
    A
    Annotation and Cross Reference  
    Feature Name
    Feature Type
    Detection Method
    Range positions
    More...
    No records found.

    C
    Participant: Nuclear mitotic apparatus protein 1

    Participant: Nuclear mitotic apparatus protein 1

    Accession: EBI-6515393

    Name: EBI-521611

    Confidences:

    Type
    Value
    No records found.

    9
    EBI-347978
     logo
    NUP62
    62 kDa nucleoporin
    Nucleoporin Nup62
    Nuclear pore glycoprotein p62
    Homo sapiens
    Organism Details

    Accession: EBI-874

    Name: human

    Description: Homo sapiens

    Cross References:

    Database
    Identifier
    Secondary identifier
    Qualifier
    human

    Expressed In Details

    Accession:

    Name:

    -
    prey
    Experimental role: prey
    Accession: EBI-58

    Name: prey

    Description: prey

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    psi-mi
    MI:0498
    -
    identity
    pubmed
    14755292
    -
    primary-reference


    Annotations:
    Topic
    Text
    definition
    Molecule experimentally identified as being captured by a given bait.


    unspecified role
    Biological role: unspecified role
    Accession: EBI-77781

    Name: unspecified role

    Description: unspecified role

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    psi-mi
    MI:0499
    -
    identity
    pubmed
    14755292
    -
    primary-reference


    Annotations:
    Topic
    Text
    definition
    Role not specified or not applicable to the data.


    protein
    Interactor type: protein
    Accession: EBI-619654

    Name: protein

    Description: protein

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    psi-mi
    MI:0326
    -
    identity
    pubmed
    14755292
    -
    primary-reference
    so
    SO:0000358
    -
    see-also


    Annotations:
    Topic
    Text
    definition
    A linear polymer of amino acids joined by peptide bonds in a specific sequence.


    A
    Participant: Nuclear pore glycoprotein p62

    Participant: Nuclear pore glycoprotein p62

    Accession: EBI-6515394

    Name: EBI-347978

    P
    Participant: Nuclear pore glycoprotein p62

    Participant: Nuclear pore glycoprotein p62

    Accession: EBI-6515394

    Name: EBI-347978

    Parameters:

    Type
    Value
    Unit
    Base
    Exponent
    Uncertainty
    No records found.


    S
    Participant: Nuclear pore glycoprotein p62

    Participant: Nuclear pore glycoprotein p62

    Accession: EBI-6515394

    Name: EBI-347978

    Stoichiometry: 0.0

    F
    Participant: Nuclear pore glycoprotein p62

    Participant: Nuclear pore glycoprotein p62

    Accession: EBI-6515394

    Name: EBI-347978

    Features:

    Legend:
    A
    Annotation and Cross Reference  
    Feature Name
    Feature Type
    Detection Method
    Range positions
    More...
    No records found.

    C
    Participant: Nuclear pore glycoprotein p62

    Participant: Nuclear pore glycoprotein p62

    Accession: EBI-6515394

    Name: EBI-347978

    Confidences:

    Type
    Value
    No records found.

    10
    EBI-2371082
     logo
    NUP50
    NPAP60L
    Nuclear pore-associated protein 60 kDa-like

    [+3]
    Nuclear pore complex protein Nup50
    Homo sapiens
    Organism Details

    Accession: EBI-874

    Name: human

    Description: Homo sapiens

    Cross References:

    Database
    Identifier
    Secondary identifier
    Qualifier
    human

    Expressed In Details

    Accession:

    Name:

    -
    prey
    Experimental role: prey
    Accession: EBI-58

    Name: prey

    Description: prey

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    psi-mi
    MI:0498
    -
    identity
    pubmed
    14755292
    -
    primary-reference


    Annotations:
    Topic
    Text
    definition
    Molecule experimentally identified as being captured by a given bait.


    unspecified role
    Biological role: unspecified role
    Accession: EBI-77781

    Name: unspecified role

    Description: unspecified role

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    psi-mi
    MI:0499
    -
    identity
    pubmed
    14755292
    -
    primary-reference


    Annotations:
    Topic
    Text
    definition
    Role not specified or not applicable to the data.


    protein
    Interactor type: protein
    Accession: EBI-619654

    Name: protein

    Description: protein

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    psi-mi
    MI:0326
    -
    identity
    pubmed
    14755292
    -
    primary-reference
    so
    SO:0000358
    -
    see-also


    Annotations:
    Topic
    Text
    definition
    A linear polymer of amino acids joined by peptide bonds in a specific sequence.


    A
    Participant: Nuclear pore complex protein Nup50

    Participant: Nuclear pore complex protein Nup50

    Accession: EBI-6515395

    Name: EBI-2371082

    P
    Participant: Nuclear pore complex protein Nup50

    Participant: Nuclear pore complex protein Nup50

    Accession: EBI-6515395

    Name: EBI-2371082

    Parameters:

    Type
    Value
    Unit
    Base
    Exponent
    Uncertainty
    No records found.


    S
    Participant: Nuclear pore complex protein Nup50

    Participant: Nuclear pore complex protein Nup50

    Accession: EBI-6515395

    Name: EBI-2371082

    Stoichiometry: 0.0

    F
    Participant: Nuclear pore complex protein Nup50

    Participant: Nuclear pore complex protein Nup50

    Accession: EBI-6515395

    Name: EBI-2371082

    Features:

    Legend:
    A
    Annotation and Cross Reference  
    Feature Name
    Feature Type
    Detection Method
    Range positions
    More...
    No records found.

    C
    Participant: Nuclear pore complex protein Nup50

    Participant: Nuclear pore complex protein Nup50

    Accession: EBI-6515395

    Name: EBI-2371082

    Confidences:

    Type
    Value
    No records found.

    11
    EBI-1048528
     logo
    TPR
    Megator
    NPC-associated intranuclear protein

    [+1]
    Nucleoprotein TPR
    Homo sapiens
    Organism Details

    Accession: EBI-874

    Name: human

    Description: Homo sapiens

    Cross References:

    Database
    Identifier
    Secondary identifier
    Qualifier
    human

    Expressed In Details

    Accession:

    Name:

    -
    prey
    Experimental role: prey
    Accession: EBI-58

    Name: prey

    Description: prey

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    psi-mi
    MI:0498
    -
    identity
    pubmed
    14755292
    -
    primary-reference


    Annotations:
    Topic
    Text
    definition
    Molecule experimentally identified as being captured by a given bait.


    unspecified role
    Biological role: unspecified role
    Accession: EBI-77781

    Name: unspecified role

    Description: unspecified role

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    psi-mi
    MI:0499
    -
    identity
    pubmed
    14755292
    -
    primary-reference


    Annotations:
    Topic
    Text
    definition
    Role not specified or not applicable to the data.


    protein
    Interactor type: protein
    Accession: EBI-619654

    Name: protein

    Description: protein

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    psi-mi
    MI:0326
    -
    identity
    pubmed
    14755292
    -
    primary-reference
    so
    SO:0000358
    -
    see-also


    Annotations:
    Topic
    Text
    definition
    A linear polymer of amino acids joined by peptide bonds in a specific sequence.


    A
    Participant: Nucleoprotein TPR

    Participant: Nucleoprotein TPR

    Accession: EBI-6515396

    Name: EBI-1048528

    P
    Participant: Nucleoprotein TPR

    Participant: Nucleoprotein TPR

    Accession: EBI-6515396

    Name: EBI-1048528

    Parameters:

    Type
    Value
    Unit
    Base
    Exponent
    Uncertainty
    No records found.


    S
    Participant: Nucleoprotein TPR

    Participant: Nucleoprotein TPR

    Accession: EBI-6515396

    Name: EBI-1048528

    Stoichiometry: 0.0

    F
    Participant: Nucleoprotein TPR

    Participant: Nucleoprotein TPR

    Accession: EBI-6515396

    Name: EBI-1048528

    Features:

    Legend:
    A
    Annotation and Cross Reference  
    Feature Name
    Feature Type
    Detection Method
    Range positions
    More...
    No records found.

    C
    Participant: Nucleoprotein TPR

    Participant: Nucleoprotein TPR

    Accession: EBI-6515396

    Name: EBI-1048528

    Confidences:

    Type
    Value
    No records found.

    12
    EBI-286779
     logo
    Nucleoporin Nup153
    153 kDa nucleoporin
    NUP153
    Nuclear pore complex protein Nup153
    Homo sapiens
    Organism Details

    Accession: EBI-874

    Name: human

    Description: Homo sapiens

    Cross References:

    Database
    Identifier
    Secondary identifier
    Qualifier
    human

    Expressed In Details

    Accession:

    Name:

    -
    prey
    Experimental role: prey
    Accession: EBI-58

    Name: prey

    Description: prey

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    psi-mi
    MI:0498
    -
    identity
    pubmed
    14755292
    -
    primary-reference


    Annotations:
    Topic
    Text
    definition
    Molecule experimentally identified as being captured by a given bait.


    unspecified role
    Biological role: unspecified role
    Accession: EBI-77781

    Name: unspecified role

    Description: unspecified role

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    psi-mi
    MI:0499
    -
    identity
    pubmed
    14755292
    -
    primary-reference


    Annotations:
    Topic
    Text
    definition
    Role not specified or not applicable to the data.


    protein
    Interactor type: protein
    Accession: EBI-619654

    Name: protein

    Description: protein

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    psi-mi
    MI:0326
    -
    identity
    pubmed
    14755292
    -
    primary-reference
    so
    SO:0000358
    -
    see-also


    Annotations:
    Topic
    Text
    definition
    A linear polymer of amino acids joined by peptide bonds in a specific sequence.


    A
    Participant: Nuclear pore complex protein Nup153

    Participant: Nuclear pore complex protein Nup153

    Accession: EBI-6515397

    Name: EBI-286779

    P
    Participant: Nuclear pore complex protein Nup153

    Participant: Nuclear pore complex protein Nup153

    Accession: EBI-6515397

    Name: EBI-286779

    Parameters:

    Type
    Value
    Unit
    Base
    Exponent
    Uncertainty
    No records found.


    S
    Participant: Nuclear pore complex protein Nup153

    Participant: Nuclear pore complex protein Nup153

    Accession: EBI-6515397

    Name: EBI-286779

    Stoichiometry: 0.0

    F
    Participant: Nuclear pore complex protein Nup153

    Participant: Nuclear pore complex protein Nup153

    Accession: EBI-6515397

    Name: EBI-286779

    Features:

    Legend:
    A
    Annotation and Cross Reference  
    Feature Name
    Feature Type
    Detection Method
    Range positions
    More...
    No records found.

    C
    Participant: Nuclear pore complex protein Nup153

    Participant: Nuclear pore complex protein Nup153

    Accession: EBI-6515397

    Name: EBI-286779

    Confidences:

    Type
    Value
    No records found.

    13
    EBI-973138
     logo
    RANBP2
    NUP358
    Ran-binding protein 2

    [+4]
    E3 SUMO-protein ligase RanBP2
    Homo sapiens
    Organism Details

    Accession: EBI-874

    Name: human

    Description: Homo sapiens

    Cross References:

    Database
    Identifier
    Secondary identifier
    Qualifier
    human

    Expressed In Details

    Accession:

    Name:

    -
    prey
    Experimental role: prey
    Accession: EBI-58

    Name: prey

    Description: prey

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    psi-mi
    MI:0498
    -
    identity
    pubmed
    14755292
    -
    primary-reference


    Annotations:
    Topic
    Text
    definition
    Molecule experimentally identified as being captured by a given bait.


    unspecified role
    Biological role: unspecified role
    Accession: EBI-77781

    Name: unspecified role

    Description: unspecified role

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    psi-mi
    MI:0499
    -
    identity
    pubmed
    14755292
    -
    primary-reference


    Annotations:
    Topic
    Text
    definition
    Role not specified or not applicable to the data.


    protein
    Interactor type: protein
    Accession: EBI-619654

    Name: protein

    Description: protein

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    psi-mi
    MI:0326
    -
    identity
    pubmed
    14755292
    -
    primary-reference
    so
    SO:0000358
    -
    see-also


    Annotations:
    Topic
    Text
    definition
    A linear polymer of amino acids joined by peptide bonds in a specific sequence.


    A
    Participant: E3 SUMO-protein ligase RanBP2

    Participant: E3 SUMO-protein ligase RanBP2

    Accession: EBI-6515398

    Name: EBI-973138

    P
    Participant: E3 SUMO-protein ligase RanBP2

    Participant: E3 SUMO-protein ligase RanBP2

    Accession: EBI-6515398

    Name: EBI-973138

    Parameters:

    Type
    Value
    Unit
    Base
    Exponent
    Uncertainty
    No records found.


    S
    Participant: E3 SUMO-protein ligase RanBP2

    Participant: E3 SUMO-protein ligase RanBP2

    Accession: EBI-6515398

    Name: EBI-973138

    Stoichiometry: 0.0

    F
    Participant: E3 SUMO-protein ligase RanBP2

    Participant: E3 SUMO-protein ligase RanBP2

    Accession: EBI-6515398

    Name: EBI-973138

    Features:

    Legend:
    A
    Annotation and Cross Reference  
    Feature Name
    Feature Type
    Detection Method
    Range positions
    More...
    No records found.

    C
    Participant: E3 SUMO-protein ligase RanBP2

    Participant: E3 SUMO-protein ligase RanBP2

    Accession: EBI-6515398

    Name: EBI-973138

    Confidences:

    Type
    Value
    No records found.

    14
    EBI-1032909
     logo
    RANBP1
    Ran-binding protein 1
    Ran-specific GTPase-activating protein
    Homo sapiens
    Organism Details

    Accession: EBI-874

    Name: human

    Description: Homo sapiens

    Cross References:

    Database
    Identifier
    Secondary identifier
    Qualifier
    human

    Expressed In Details

    Accession:

    Name:

    -
    prey
    Experimental role: prey
    Accession: EBI-58

    Name: prey

    Description: prey

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    psi-mi
    MI:0498
    -
    identity
    pubmed
    14755292
    -
    primary-reference


    Annotations:
    Topic
    Text
    definition
    Molecule experimentally identified as being captured by a given bait.


    unspecified role
    Biological role: unspecified role
    Accession: EBI-77781

    Name: unspecified role

    Description: unspecified role

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    psi-mi
    MI:0499
    -
    identity
    pubmed
    14755292
    -
    primary-reference


    Annotations:
    Topic
    Text
    definition
    Role not specified or not applicable to the data.


    protein
    Interactor type: protein
    Accession: EBI-619654

    Name: protein

    Description: protein

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    psi-mi
    MI:0326
    -
    identity
    pubmed
    14755292
    -
    primary-reference
    so
    SO:0000358
    -
    see-also


    Annotations:
    Topic
    Text
    definition
    A linear polymer of amino acids joined by peptide bonds in a specific sequence.


    A
    Participant: Ran-specific GTPase-activating protein

    Participant: Ran-specific GTPase-activating protein

    Accession: EBI-6515399

    Name: EBI-1032909

    P
    Participant: Ran-specific GTPase-activating protein

    Participant: Ran-specific GTPase-activating protein

    Accession: EBI-6515399

    Name: EBI-1032909

    Parameters:

    Type
    Value
    Unit
    Base
    Exponent
    Uncertainty
    No records found.


    S
    Participant: Ran-specific GTPase-activating protein

    Participant: Ran-specific GTPase-activating protein

    Accession: EBI-6515399

    Name: EBI-1032909

    Stoichiometry: 0.0

    F
    Participant: Ran-specific GTPase-activating protein

    Participant: Ran-specific GTPase-activating protein

    Accession: EBI-6515399

    Name: EBI-1032909

    Features:

    Legend:
    A
    Annotation and Cross Reference  
    Feature Name
    Feature Type
    Detection Method
    Range positions
    More...
    No records found.

    C
    Participant: Ran-specific GTPase-activating protein

    Participant: Ran-specific GTPase-activating protein

    Accession: EBI-6515399

    Name: EBI-1032909

    Confidences:

    Type
    Value
    No records found.

    15
    EBI-876367
     logo
    MKI67
    Antigen KI-67
    Homo sapiens
    Organism Details

    Accession: EBI-874

    Name: human

    Description: Homo sapiens

    Cross References:

    Database
    Identifier
    Secondary identifier
    Qualifier
    human

    Expressed In Details

    Accession:

    Name:

    -
    prey
    Experimental role: prey
    Accession: EBI-58

    Name: prey

    Description: prey

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    psi-mi
    MI:0498
    -
    identity
    pubmed
    14755292
    -
    primary-reference


    Annotations:
    Topic
    Text
    definition
    Molecule experimentally identified as being captured by a given bait.


    unspecified role
    Biological role: unspecified role
    Accession: EBI-77781

    Name: unspecified role

    Description: unspecified role

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    psi-mi
    MI:0499
    -
    identity
    pubmed
    14755292
    -
    primary-reference


    Annotations:
    Topic
    Text
    definition
    Role not specified or not applicable to the data.


    protein
    Interactor type: protein
    Accession: EBI-619654

    Name: protein

    Description: protein

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    psi-mi
    MI:0326
    -
    identity
    pubmed
    14755292
    -
    primary-reference
    so
    SO:0000358
    -
    see-also


    Annotations:
    Topic
    Text
    definition
    A linear polymer of amino acids joined by peptide bonds in a specific sequence.


    A
    Participant: Antigen KI-67

    Participant: Antigen KI-67

    Accession: EBI-6515400

    Name: EBI-876367

    P
    Participant: Antigen KI-67

    Participant: Antigen KI-67

    Accession: EBI-6515400

    Name: EBI-876367

    Parameters:

    Type
    Value
    Unit
    Base
    Exponent
    Uncertainty
    No records found.


    S
    Participant: Antigen KI-67

    Participant: Antigen KI-67

    Accession: EBI-6515400

    Name: EBI-876367

    Stoichiometry: 0.0

    F
    Participant: Antigen KI-67

    Participant: Antigen KI-67

    Accession: EBI-6515400

    Name: EBI-876367

    Features:

    Legend:
    A
    Annotation and Cross Reference  
    Feature Name
    Feature Type
    Detection Method
    Range positions
    More...
    No records found.

    C
    Participant: Antigen KI-67

    Participant: Antigen KI-67

    Accession: EBI-6515400

    Name: EBI-876367

    Confidences:

    Type
    Value
    No records found.

    16
    EBI-295890
     logo
    PML
    MYL
    RNF71

    [+5]
    Protein PML
    Homo sapiens
    Organism Details

    Accession: EBI-874

    Name: human

    Description: Homo sapiens

    Cross References:

    Database
    Identifier
    Secondary identifier
    Qualifier
    human

    Expressed In Details

    Accession:

    Name:

    -
    prey
    Experimental role: prey
    Accession: EBI-58

    Name: prey

    Description: prey

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    psi-mi
    MI:0498
    -
    identity
    pubmed
    14755292
    -
    primary-reference


    Annotations:
    Topic
    Text
    definition
    Molecule experimentally identified as being captured by a given bait.


    unspecified role
    Biological role: unspecified role
    Accession: EBI-77781

    Name: unspecified role

    Description: unspecified role

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    psi-mi
    MI:0499
    -
    identity
    pubmed
    14755292
    -
    primary-reference


    Annotations:
    Topic
    Text
    definition
    Role not specified or not applicable to the data.


    protein
    Interactor type: protein
    Accession: EBI-619654

    Name: protein

    Description: protein

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    psi-mi
    MI:0326
    -
    identity
    pubmed
    14755292
    -
    primary-reference
    so
    SO:0000358
    -
    see-also


    Annotations:
    Topic
    Text
    definition
    A linear polymer of amino acids joined by peptide bonds in a specific sequence.


    A
    Participant: Protein PML

    Participant: Protein PML

    Accession: EBI-6515401

    Name: EBI-295890

    P
    Participant: Protein PML

    Participant: Protein PML

    Accession: EBI-6515401

    Name: EBI-295890

    Parameters:

    Type
    Value
    Unit
    Base
    Exponent
    Uncertainty
    No records found.


    S
    Participant: Protein PML

    Participant: Protein PML

    Accession: EBI-6515401

    Name: EBI-295890

    Stoichiometry: 0.0

    F
    Participant: Protein PML

    Participant: Protein PML

    Accession: EBI-6515401

    Name: EBI-295890

    Features:

    Legend:
    A
    Annotation and Cross Reference  
    Feature Name
    Feature Type
    Detection Method
    Range positions
    More...
    No records found.

    C
    Participant: Protein PML

    Participant: Protein PML

    Accession: EBI-6515401

    Name: EBI-295890

    Confidences:

    Type
    Value
    No records found.

    17
    EBI-1051583
     logo
    ZRANB2
    ZIS
    ZNF265

    [+2]
    Zinc finger Ran-binding domain-containing protein 2
    Homo sapiens
    Organism Details

    Accession: EBI-874

    Name: human

    Description: Homo sapiens

    Cross References:

    Database
    Identifier
    Secondary identifier
    Qualifier
    human

    Expressed In Details

    Accession:

    Name:

    -
    prey
    Experimental role: prey
    Accession: EBI-58

    Name: prey

    Description: prey

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    psi-mi
    MI:0498
    -
    identity
    pubmed
    14755292
    -
    primary-reference


    Annotations:
    Topic
    Text
    definition
    Molecule experimentally identified as being captured by a given bait.


    unspecified role
    Biological role: unspecified role
    Accession: EBI-77781

    Name: unspecified role

    Description: unspecified role

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    psi-mi
    MI:0499
    -
    identity
    pubmed
    14755292
    -
    primary-reference


    Annotations:
    Topic
    Text
    definition
    Role not specified or not applicable to the data.


    protein
    Interactor type: protein
    Accession: EBI-619654

    Name: protein

    Description: protein

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    psi-mi
    MI:0326
    -
    identity
    pubmed
    14755292
    -
    primary-reference
    so
    SO:0000358
    -
    see-also


    Annotations:
    Topic
    Text
    definition
    A linear polymer of amino acids joined by peptide bonds in a specific sequence.


    A
    Participant: Zinc finger Ran-binding domain-containing protein 2

    Participant: Zinc finger Ran-binding domain-containing protein 2

    Accession: EBI-6515402

    Name: EBI-1051583

    P
    Participant: Zinc finger Ran-binding domain-containing protein 2

    Participant: Zinc finger Ran-binding domain-containing protein 2

    Accession: EBI-6515402

    Name: EBI-1051583

    Parameters:

    Type
    Value
    Unit
    Base
    Exponent
    Uncertainty
    No records found.


    S
    Participant: Zinc finger Ran-binding domain-containing protein 2

    Participant: Zinc finger Ran-binding domain-containing protein 2

    Accession: EBI-6515402

    Name: EBI-1051583

    Stoichiometry: 0.0

    F
    Participant: Zinc finger Ran-binding domain-containing protein 2

    Participant: Zinc finger Ran-binding domain-containing protein 2

    Accession: EBI-6515402

    Name: EBI-1051583

    Features:

    Legend:
    A
    Annotation and Cross Reference  
    Feature Name
    Feature Type
    Detection Method
    Range positions
    More...
    No records found.

    C
    Participant: Zinc finger Ran-binding domain-containing protein 2

    Participant: Zinc finger Ran-binding domain-containing protein 2

    Accession: EBI-6515402

    Name: EBI-1051583

    Confidences:

    Type
    Value
    No records found.

    18
    EBI-346967
     logo
    NCL
    Protein C23
    Nucleolin
    Homo sapiens
    Organism Details

    Accession: EBI-874

    Name: human

    Description: Homo sapiens

    Cross References:

    Database
    Identifier
    Secondary identifier
    Qualifier
    human

    Expressed In Details

    Accession:

    Name:

    -
    prey
    Experimental role: prey
    Accession: EBI-58

    Name: prey

    Description: prey

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    psi-mi
    MI:0498
    -
    identity
    pubmed
    14755292
    -
    primary-reference


    Annotations:
    Topic
    Text
    definition
    Molecule experimentally identified as being captured by a given bait.


    unspecified role
    Biological role: unspecified role
    Accession: EBI-77781

    Name: unspecified role

    Description: unspecified role

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    psi-mi
    MI:0499
    -
    identity
    pubmed
    14755292
    -
    primary-reference


    Annotations:
    Topic
    Text
    definition
    Role not specified or not applicable to the data.


    protein
    Interactor type: protein
    Accession: EBI-619654

    Name: protein

    Description: protein

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    psi-mi
    MI:0326
    -
    identity
    pubmed
    14755292
    -
    primary-reference
    so
    SO:0000358
    -
    see-also


    Annotations:
    Topic
    Text
    definition
    A linear polymer of amino acids joined by peptide bonds in a specific sequence.


    A
    Participant: Nucleolin

    Participant: Nucleolin

    Accession: EBI-6515403

    Name: EBI-346967

    P
    Participant: Nucleolin

    Participant: Nucleolin

    Accession: EBI-6515403

    Name: EBI-346967

    Parameters:

    Type
    Value
    Unit
    Base
    Exponent
    Uncertainty
    No records found.


    S
    Participant: Nucleolin

    Participant: Nucleolin

    Accession: EBI-6515403

    Name: EBI-346967

    Stoichiometry: 0.0

    F
    Participant: Nucleolin

    Participant: Nucleolin

    Accession: EBI-6515403

    Name: EBI-346967

    Features:

    Legend:
    A
    Annotation and Cross Reference  
    Feature Name
    Feature Type
    Detection Method
    Range positions
    More...
    No records found.

    C
    Participant: Nucleolin

    Participant: Nucleolin

    Accession: EBI-6515403

    Name: EBI-346967

    Confidences:

    Type
    Value
    No records found.

    19
    EBI-711331
     logo
    RIF1
    Rap1-interacting factor 1 homolog
    Telomere-associated protein RIF1
    Homo sapiens
    Organism Details

    Accession: EBI-874

    Name: human

    Description: Homo sapiens

    Cross References:

    Database
    Identifier
    Secondary identifier
    Qualifier
    human

    Expressed In Details

    Accession:

    Name:

    -
    prey
    Experimental role: prey
    Accession: EBI-58

    Name: prey

    Description: prey

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    psi-mi
    MI:0498
    -
    identity
    pubmed
    14755292
    -
    primary-reference


    Annotations:
    Topic
    Text
    definition
    Molecule experimentally identified as being captured by a given bait.


    unspecified role
    Biological role: unspecified role
    Accession: EBI-77781

    Name: unspecified role

    Description: unspecified role

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    psi-mi
    MI:0499
    -
    identity
    pubmed
    14755292
    -
    primary-reference


    Annotations:
    Topic
    Text
    definition
    Role not specified or not applicable to the data.


    protein
    Interactor type: protein
    Accession: EBI-619654

    Name: protein

    Description: protein

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    psi-mi
    MI:0326
    -
    identity
    pubmed
    14755292
    -
    primary-reference
    so
    SO:0000358
    -
    see-also


    Annotations:
    Topic
    Text
    definition
    A linear polymer of amino acids joined by peptide bonds in a specific sequence.


    A
    Participant: Telomere-associated protein RIF1

    Participant: Telomere-associated protein RIF1

    Accession: EBI-6515404

    Name: EBI-711331

    P
    Participant: Telomere-associated protein RIF1

    Participant: Telomere-associated protein RIF1

    Accession: EBI-6515404

    Name: EBI-711331

    Parameters:

    Type
    Value
    Unit
    Base
    Exponent
    Uncertainty
    No records found.


    S
    Participant: Telomere-associated protein RIF1

    Participant: Telomere-associated protein RIF1

    Accession: EBI-6515404

    Name: EBI-711331

    Stoichiometry: 0.0

    F
    Participant: Telomere-associated protein RIF1

    Participant: Telomere-associated protein RIF1

    Accession: EBI-6515404

    Name: EBI-711331

    Features:

    Legend:
    A
    Annotation and Cross Reference  
    Feature Name
    Feature Type
    Detection Method
    Range positions
    More...
    No records found.

    C
    Participant: Telomere-associated protein RIF1

    Participant: Telomere-associated protein RIF1

    Accession: EBI-6515404

    Name: EBI-711331

    Confidences:

    Type
    Value
    No records found.

    20
    EBI-396258
     logo
    ACIN1
    ACINUS
    KIAA0670
    Apoptotic chromatin condensation inducer in the nucleus
    Homo sapiens
    Organism Details

    Accession: EBI-874

    Name: human

    Description: Homo sapiens

    Cross References:

    Database
    Identifier
    Secondary identifier
    Qualifier
    human

    Expressed In Details

    Accession:

    Name:

    -
    prey
    Experimental role: prey
    Accession: EBI-58

    Name: prey

    Description: prey

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    psi-mi
    MI:0498
    -
    identity
    pubmed
    14755292
    -
    primary-reference


    Annotations:
    Topic
    Text
    definition
    Molecule experimentally identified as being captured by a given bait.


    unspecified role
    Biological role: unspecified role
    Accession: EBI-77781

    Name: unspecified role

    Description: unspecified role

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    psi-mi
    MI:0499
    -
    identity
    pubmed
    14755292
    -
    primary-reference


    Annotations:
    Topic
    Text
    definition
    Role not specified or not applicable to the data.


    protein
    Interactor type: protein
    Accession: EBI-619654

    Name: protein

    Description: protein

    Cross References:
    Database
    Identifier
    Secondary identifier
    Qualifier
    psi-mi
    MI:0326
    -
    identity
    pubmed
    14755292
    -
    primary-reference
    so
    SO:0000358
    -
    see-also


    Annotations:
    Topic
    Text
    definition
    A linear polymer of amino acids joined by peptide bonds in a specific sequence.


    A
    Participant: Apoptotic chromatin condensation inducer in the nucleus

    Participant: Apoptotic chromatin condensation inducer in the nucleus

    Accession: EBI-6515405

    Name: EBI-396258

    P
    Participant: Apoptotic chromatin condensation inducer in the nucleus

    Participant: Apoptotic chromatin condensation inducer in the nucleus

    Accession: EBI-6515405

    Name: EBI-396258

    Parameters:

    Type
    Value
    Unit
    Base
    Exponent
    Uncertainty
    No records found.


    S
    Participant: Apoptotic chromatin condensation inducer in the nucleus

    Participant: Apoptotic chromatin condensation inducer in the nucleus

    Accession: EBI-6515405

    Name: EBI-396258

    Stoichiometry: 0.0

    F
    Participant: Apoptotic chromatin condensation inducer in the nucleus

    Participant: Apoptotic chromatin condensation inducer in the nucleus

    Accession: EBI-6515405

    Name: EBI-396258

    Features:

    Legend:
    A
    Annotation and Cross Reference  
    Feature Name
    Feature Type
    Detection Method
    Range positions
    More...
    No records found.

    C
    Participant: Apoptotic chromatin condensation inducer in the nucleus

    Participant: Apoptotic chromatin condensation inducer in the nucleus

    Accession: EBI-6515405

    Name: EBI-396258

    Confidences:

    Type
    Value
    No records found.


    Graphical Representation of Experimental Features